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  •   University of Thessaly Institutional Repository
  • Επιστημονικές Δημοσιεύσεις Μελών ΠΘ (ΕΔΠΘ)
  • Δημοσιεύσεις σε περιοδικά, συνέδρια, κεφάλαια βιβλίων κλπ.
  • View Item
  •   University of Thessaly Institutional Repository
  • Επιστημονικές Δημοσιεύσεις Μελών ΠΘ (ΕΔΠΘ)
  • Δημοσιεύσεις σε περιοδικά, συνέδρια, κεφάλαια βιβλίων κλπ.
  • View Item
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Role of Prophylactic Antibiotics in Uncontaminated Neck Dissections

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Author
Carrau, R. L.; Byzakis, J.; Wagner, R. L.; Johnson, J. T.
Date
1991
DOI
10.1001/archotol.1991.01870140082011
Keyword
antibiotic agent
article
diagnosis
drug therapy
etiology
head and neck cancer
human
infection
major clinical study
neck dissection
priority journal
surgery
Adult
Aged
Aged, 80 and over
Antibiotics
Female
Male
Middle Age
Premedication
Retrospective Studies
Surgical Wound Infection
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Abstract
The use of perioperative prophylactic antibiotics in uncontaminated head and neck surgery remains controversial. We performed a retrospective analysis of 192 patients undergoing uncontaminated neck dissections from 1976 to 1989. Wound infection developed in 10% (10/99) of patients who did not receive antibiotics, while only three (3.3%) of 93 patients who received antibiotics developed infections. This difference was not statistically significant. We correlated the use of flaps, length of surgery, prior radiation treatment, and postoperative complications with rate of wound infection. The difference was not statistically significant for any of these variables. Our β error was, however, greater than 0.2. Our data do not demonstrate efficacy of prophylactic antibiotics in uncontaminated neck dissections with statistical significance; however, a trend exists suggesting its possible value. © 1991, American Medical Association. All rights reserved.
URI
http://hdl.handle.net/11615/26514
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  • Δημοσιεύσεις σε περιοδικά, συνέδρια, κεφάλαια βιβλίων κλπ. [19674]
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