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The Fat Content of Small Primary Breast Cancer Interferes with Radiofrequency-Induced Thermal Ablation
dc.creator | Athanassiou, E. | en |
dc.creator | Sioutopoulou, D. | en |
dc.creator | Vamvakopoulos, N. | en |
dc.creator | Karasavvidou, F. | en |
dc.creator | Tzovaras, G. | en |
dc.creator | Tziastoudi, E. | en |
dc.creator | Sakellariou, M. | en |
dc.creator | Hatzitheofilou, C. | en |
dc.date.accessioned | 2015-11-23T10:23:18Z | |
dc.date.available | 2015-11-23T10:23:18Z | |
dc.date.issued | 2009 | |
dc.identifier | 10.1159/000168318 | |
dc.identifier.issn | 0014-312X | |
dc.identifier.uri | http://hdl.handle.net/11615/26033 | |
dc.description.abstract | Background: Radiofrequency (RF) thermal ablation is a minimally invasive technique of local mass elimination with variable efficiency. Methods: Ten patients with small primary breast cancer diagnosed preoperatively by core needle biopsy were ablated percutaneously by an RF (Radionics Cool-tip) device operating on impedance control mode. The percent fat-containing area was calculated in each slide of a total of 47 slides introduced to IQ materials software image analysis. Results: Seven of 10 tumors with tumor diameter less than 2.8 cm and fat content less than 12.47% were totally ablated ( score 3). One of 10 with 3 cm tumor diameter and 5.45% fat content showed an intermediate degree of ablated tissue ( score 2), and the last 2 with 2 cm and 2.2 cm tumor diameter and more than 19.74% tumor fat content were minimally ablated ( score 1). Our present exploratory study on 10 patients suggests dependence of the degree of thermal damage on tumor fat content. Conclusions: We conclude that the fat content of small primary breast cancer could serve as a 'heat sink' and should be considered as a preventing factor of complete local tumor destruction by RF thermal ablation. Copyright (c) 2008 S. Karger AG, Basel | en |
dc.source | European Surgical Research | en |
dc.source.uri | <Go to ISI>://WOS:000261292600009 | |
dc.subject | Breast cancer | en |
dc.subject | Tumor ablation | en |
dc.subject | Fat content | en |
dc.subject | Computer software analysis | en |
dc.subject | CARCINOMA | en |
dc.subject | Surgery | en |
dc.title | The Fat Content of Small Primary Breast Cancer Interferes with Radiofrequency-Induced Thermal Ablation | en |
dc.type | journalArticle | en |
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