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Postpartal recurrent non-ST elevation myocardial infarction in essential thrombocythaemia: Case report and review of the literature

dc.creatorArampatzis, S.en
dc.creatorStefanidis, I.en
dc.creatorLakiopoulos, V.en
dc.creatorRaio, L.en
dc.creatorSurbek, D.en
dc.creatorMohaupt, M. G.en
dc.date.accessioned2015-11-23T10:22:43Z
dc.date.available2015-11-23T10:22:43Z
dc.date.issued2010
dc.identifier10.1186/1477-9560-8-12
dc.identifier.issn14779560
dc.identifier.urihttp://hdl.handle.net/11615/25743
dc.description.abstractNormal pregnancy corresponds to a procoagulant state. Acute myocardial infarction during pregnancy is rare, yet considering the low non-pregnant risk score of childbearing women it is still surprisingly frequent. We report a case of postpartum recurrent non-ST elevation myocardial infarction in a 40-year-old caucasian woman with essential thrombocythaemia in the presence of a positive JAK-2 mutation and an elevated anti-cardiolipin IgM antibody titer. In the majority of cases of myocardial infarction in pregnancy or in the peripartal period, atherosclerosis, a thrombus or coronary artery dissection is observed. The combination of essential thrombocythaemia and elevated anti-cardiolipin IgM antibody titer in the presence of several cardiovascular risk factors seems to be causative in our case. In conclusion, with the continuing trend of childbearing at older ages, rare or unlikely conditions leading to severe events such as myocardial infarction must be considered in pregnant women.© 2010 Arampatzis et al; licensee BioMed Central Ltd.en
dc.sourceThrombosis Journalen
dc.source.urihttp://www.scopus.com/inward/record.url?eid=2-s2.0-77953567602&partnerID=40&md5=b3357602f1add65555c1ba7df38b21ed
dc.subjectacetylsalicylic aciden
dc.subjectamlodipineen
dc.subjectcardiolipin antibodyen
dc.subjectclopidogrelen
dc.subjectcreatine kinaseen
dc.subjectglyceryl trinitrateen
dc.subjectheparinen
dc.subjecthydroxyureaen
dc.subjectimmunoglobulin M antibodyen
dc.subjectJanus kinase 2en
dc.subjectmetoprololen
dc.subjectsimvastatinen
dc.subjecttroponin Ten
dc.subjectadulten
dc.subjectangiocardiographyen
dc.subjectantibody titeren
dc.subjectartery dissectionen
dc.subjectarticleen
dc.subjectatherosclerosisen
dc.subjectcardiovascular risken
dc.subjectcase reporten
dc.subjectCaucasianen
dc.subjectcesarean sectionen
dc.subjectcomputed tomographic angiographyen
dc.subjectechocardiographyen
dc.subjectfamily historyen
dc.subjectfemaleen
dc.subjectgene mutationen
dc.subjecthumanen
dc.subjecthypertensionen
dc.subjectintrauterine growth retardationen
dc.subjectnon ST segment elevation myocardial infarctionen
dc.subjectnuclear magnetic resonance scanneren
dc.subjectpuerperiumen
dc.subjectrecurrent diseaseen
dc.subjectthorax radiographyen
dc.subjectthrombocyte counten
dc.subjectthrombocythemiaen
dc.subjectthrombusen
dc.subjecttransesophageal echocardiographyen
dc.titlePostpartal recurrent non-ST elevation myocardial infarction in essential thrombocythaemia: Case report and review of the literatureen
dc.typejournalArticleen


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