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Association of the leptin gene with knee osteoarthritis susceptibility in a Han Chinese population: A case-control study
(2010)
Previous studies have suggested that leptin works as a key regulator in the pathogenesis of osteoarthritis (OA), and genetic factors modulate OA. This study assessed the contribution of leptin gene (LEP) polymorphism(s) ...
Large replication study and meta-analyses of DVWA as an osteoarthritis susceptibility locus in European and Asian populations
(2009)
Recently, through a genome wide association study in Japanese knee osteoarthritis (OA) cases, a previously unknown gene, DVWA, was identified. The non-synonymous single nucleotide polymorphism (SNP) rs7639618 was subsequently ...
A large-scale replication study for the association of rs17039192 in HIF-2 alpha with knee osteoarthritis
(2012)
Osteoarthritis (OA) is a common disease with a genetic component for its etiology. Recently, a genetic association of a single nucleotide polymorphism (SNP), rs17039192 in HIF-2a with knee OA has been reported in a Japanese ...