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Aldehyde dehydrogenase 1B1: Molecular cloning and characterization of a novel mitochondrial acetaldehyde-metabolizing enzyme
(2010)
Ethanol-induced damage is largely attributed to its toxic metabolite, acetaldehyde. Clearance of acetaldehyde is achieved by its oxidation, primarily catalyzed by the mitochondrial class II aldehyde dehydrogenase (ALDH2). ...
Ticagrelor and prasugrel: Two novel, most-promising antiplatelet agents
(2010)
The need for safe and effective antiplatelet agents motivates scientists towards a non-ceasing research which has through the past few years provided patients suffering from coronary artery disease, submitted or not to ...
Letter to the editor [2]
(2010)
Convergence of linkage, gene expression and association data demonstrates the influence of the RAR-related orphan receptor alpha (RORA) gene on neovascular AMD: A systems biology based approach
(2010)
To identify novel genes and pathways associated with AMD, we performed microarray gene expression and linkage analysis which implicated the candidate gene, retinoic acid receptor-related orphan receptor alpha (RORA, 15q). ...
Dimerization of the AtoC response regulator and modelling of its binding to DNA
(2010)
Bacterial signal transduction systems can be viewed as an entity of multi-sensory and output domains, whereas the functions of response regulators play a pivotal role in the complex network interactions. One crucial property ...
Social relationships of pupils with special educational needs in the mainstream primary class: Peer group membership and peer-assessed social behaviour
(2010)
One of the major aims for the inclusion of pupils with special educational needs (SEN) within the mainstream classroom is to reduce prejudice and increase social interaction among children. Nevertheless, research has ...
T-cells and B-cells in systemic sclerosis
(2010)
Systemic sclerosis (SSc) is characterized by activation of fibroblasts with extensive deposition of collagen, by small vessel vasculopathy with fibrointimal proliferation, and activation of the immune system, with hyper-γ- ...
Myocardial bridging evaluated with 128-multi detector computed tomography coronary angiography
(2010)
Purpose: The aim of the study was to evaluate the prevalence, length, depth, and location of myocardial bridging of the coronary arteries using 128-multi detector computed tomography coronary angiography. Methods: The study ...
Downregulation of serum epidermal growth factor in patients with inflammatory bowel disease. Is there a link with mucosal damage?
(2010)
Background: Epidermal growth factor (EGF) is a multipotent peptide which contributes to epithelial development, inhibition of gastric acid secretion, acceleration of wound healing, and promotion of angiogenesis. The aim ...