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Oxytocin is not important for the control of gonadotrophin secretion in the late follicular phase of the cycle
(2007)
Objective To study the role of oxytocin in basal and GnRH-induced gonadotrophin secretion in normal women. Design Normal women were studied in three cycles. When the diameter of the leading follicle was 15-16 mm, the women ...
Treatment of normal women with oestradiol plus progesterone prevents the decrease of leptin concentrations induced by ovariectomy
(2000)
To study the role of oestradiol and progesterone in the secretion of leptin, 21 normally ovulating women were recruited from those scheduled for ovariectomy plus hysterectomy performed in mid-follicular phase of the cycle. ...
Oestradiol plus progesterone treatment increases serum leptin concentrations in normal women
(2001)
BACKGROUND: Previous studies have alluded to a role for both oestradiol and progesterone in the secretion of leptin from fat cells in the human, although direct evidence has yet to be obtained. The study aim was to assess ...
In vitro responsiveness of human post-menopausal myometrium to endothelin-1 and ovarian steroids
(2005)
It has been shown in vitro that endothelin 1 (ET1) differentially affects the human myometrial contractility according to the hormonal profile of women. Our purpose was to test the hypothesis that ovarian steroids influence ...
Evidence of differential control of FSH and LH responses to GnRH by ovarian steroids in the luteal phase of the cycle
(2002)
BACKGROUND: It is known that during the follicular phase of the cycle, estradiol sensitizes the pituitary to GnRH. The aim of this study was to determine the role of ovarian steroids in the control of GnRH-induced gonadotrophin ...
Changes in pituitary sensitivity to GnRH in estrogen-treated post-menopausal women: evidence that gonadotrophin surge attenuating factor plays a physiological role
(2004)
BACKGROUND: The purpose of this study was to investigate changes in pituitary response to GnRH in post-menopausal women during substitution treatment with exogenous estrogen and progesterone. METHODS: Seven healthy ...
Evidence that termination of the estradiol-induced luteinizing hormone surge in women is regulated by ovarian factors
(2006)
Background: The endogenous LH surge is the result of the estrogen-positive feedback effect. However, the factors that are responsible for the termination of LH surge are not known. Objective: The objective of the study was ...
Ovarian regulators of gonadotropin secretion
(2000)
Great progress in the ovarian mechanisms that control gonadotrophin secretion in women has recently been achieved, Estradiol (E-2) is the main component of the ovarian negative effect on basal gonadotropin secretion during ...
In vitro effects of endothelin-1 on the contractility of myometrium obtained from pre- and postmenopausal women
(2001)
This study was conducted to evaluate the responsiveness of human nonpregnant myometrium to endothelin 1 (ET1) (10(-10) M-10(-6) M) and KCl (80 mM) in relation to the hormonal profile of the women, who were allocated into ...
FSH and LH responses to GnRH after ovariectomy in postmenopausal women
(2004)
OBJECTIVE Whether the postmenopausal ovary is still playing a role in the control of gonadotrophin secretion in response to GnRH has not been investigated. The aim of the present study was to test this hypothesis by examining ...