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Treatment of normal women with oestradiol plus progesterone prevents the decrease of leptin concentrations induced by ovariectomy
(2000)
To study the role of oestradiol and progesterone in the secretion of leptin, 21 normally ovulating women were recruited from those scheduled for ovariectomy plus hysterectomy performed in mid-follicular phase of the cycle. ...
Oestradiol plus progesterone treatment increases serum leptin concentrations in normal women
(2001)
BACKGROUND: Previous studies have alluded to a role for both oestradiol and progesterone in the secretion of leptin from fat cells in the human, although direct evidence has yet to be obtained. The study aim was to assess ...
Modulating effect of leptin on basal and follicle stimulating hormone stimulated steroidogenesis in cultured human lutein granulosa cells
(2009)
Background: In vitro data have shown conflicting results in terms of the effect of leptin on granulosa cells steroidogenesis. Aim: The aim of the present study was to investigate the effect of low and high doses of leptin ...
Growth hormone, insulin-like growth factor I, and leptin interaction in human cultured lutein granulosa cells steroidogenesis
(2008)
Objective: To investigate the effect of leptin on the actions of growth hormone (GH) and insulin-like growth factor-I (IGF-I) in ovarian steroidogenesis in vitro. Design: In vitro cell culture study. Setting: Research ...
Endothelin-3 and PRL levels in the maternal and fetal circulation at delivery
(2007)
Objective: The aim of the present cross-sectional study was to test the hypothesis that endothelin-3 (ET-3) is involved in PRL secretion via systemic hormonal interaction during labor. Materials and methods: Fifty healthy ...
Evidence of differential control of FSH and LH responses to GnRH by ovarian steroids in the luteal phase of the cycle
(2002)
BACKGROUND: It is known that during the follicular phase of the cycle, estradiol sensitizes the pituitary to GnRH. The aim of this study was to determine the role of ovarian steroids in the control of GnRH-induced gonadotrophin ...
Absence of leptin expression and secretion by human luteinized granulosa cells
(2003)
Whether leptin is secreted by the human ovary is not known. The available data on leptin gene (ob gene) expression by human granulosa cells are conflicting. The aim of the present study was first to re-examine the expression ...