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Alterations of Deadenylase Expression in Acute Leukemias: Evidence for Poly(A)-Specific Ribonuclease as a Potential Biomarker
(2012)
Background/Aims: The degradation of mRNA is a key process in the control of gene expression correlated to anomalous cell proliferation. The rate-limiting step of mRNA degradation is the removal of the poly(A) tail by ...
The DJ-1 protein as a candidate biomarker in obstructive sleep apnea syndrome
(2014)
Oxidative stress has a central role in the pathophysiology of obstructive sleep apnea syndrome (OSAS). The DJ-1 protein functions as a sensor of oxidative stress, acting both as a reactive oxygen species scavenger (ROS) ...
Dexamethasone acutely accelerates pleural fluid absorption in mice hydrothoraces
(2010)
This study assessed the effect of corticosteroid treatment in the clearance of hydrothoraces in mice. Twentyfour C57BL/6 mice were divided into four groups and were injected intrapleurally with 500 mu L sterilized PBS-BSA ...
Airways microbiota: Hidden Trojan horses in asbestos exposed individuals?
(2014)
Malignant pleura mesothelioma (MPM) is a rare type of cancer with devastating prognosis, which develops in the pleural cavity from transformed mesothelium. MPM has been directly associated with asbestos exposure however ...
Matrix Metalloproteinase Levels in the Differentiation of Parapneumonic Pleural Effusions
(2010)
Background: Matrix metalloproteinases (MMPs) have been implicated in the escalation of fibrosis and remodeling which are central to the subsequent progression of a parapneumonic pleural effusion to empyema. Objectives: The ...
Plasma leptin and adiponectin in COPD exacerbations: Associations with inflammatory biomarkers
(2010)
Background: Various systemic inflammatory markers have been evaluated for their value in acute exacerbations of chronic obstructive pulmonary disease (COPD). Leptin and adiponectin have been linked to acute exacerbations ...
Permeability Alterations after Surgical Trauma in Normal Rabbit Peritoneum
(2010)
Background: To investigate whether surgical trauma in a rabbit adhesion formation model and the administration of normal saline (N/S), icodextrin (ID) and/or dimetindene maleate (DM) changes the permeability of the normal ...