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Involvement of SOX-9 and FGF-23 in RUNX-2 regulation in osteoarthritic chondrocytes
(2009)
Chondrocytes' hypertrophy includes metabolic changes, matrix remodelling, proliferation and apoptosis, characteristics associated with the progression of osteoarthritis. We investigated a possible association among ...
Proteomics of osteoarthritic chondrocytes and cartilage
(2010)
Osteoarthritis (OA) is characterized by irreversible destruction of the articular cartilage. OA affects more than 100 million individuals worldwide and has a major impact on patients' quality of life. The lack of effective ...
Impaired Expression of Genes Regulating Cholesterol Efflux in Human Osteoarthritic Chondrocytes
(2010)
Altered lipid metabolism has been implicated as a critical player in osteoarthritis (OA). Our study aimed to investigate the expression of genes regulating cholesterol efflux in human chondrocytes and to study the effect ...