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VEGF increases the permeability of sheep pleura ex vivo through VEGFR2 stimulation
(2014)
Vascular endothelial growth factor (VEGF), a cytokine that increases vascular permeability to water and proteins and induces angiogenesis, has been implicated in the development of pleural effusions. Inflammatory and ...
Insulin NO-dependent action on airways smooth muscles
(2001)
In order to find out how insulin acts on airway smooth muscle and which mechanisms could be involved, we studied the effect of insulin on contraction induced, first, by KCI and, second, by Acetylcholine (Ach), before and ...
Airway responsiveness: role of inflammation, epithelium damage and smooth muscle tension
(1999)
THE purpose of this study was the effect of epithelium damage on mechanical responses of airway smooth muscles under different resting tension. We performed acetylcholine (ACh) (10(-5) M)-induced contraction on tracheal ...
Role of Histamine in Altering Fluid Recycling in Normal and Post-Traumatic Rabbit Peritoneum
(2014)
This study aims to investigate if histamine induces electrochemical alterations in the normal and post-traumatic peritoneum. Peritoneal rabbit specimens were obtained before surgery and 10 days post-operatively and were ...
IGF-1 alters the human parietal pleural electrochemical profile by inhibiting ion trans-cellular transportation after interaction with its receptor
(2013)
Objective: The effect of IGF-1 in the human pleural permeability and the underlying mechanisms involved were investigated. Design: Specimens from thoracic surgical patients were mounted in Ussing chambers. Solutions ...
Effect of histamine on the electrophysiology of the human parietal pleura
(2011)
Introduction: Histamine is involved in the pathogenesis of numerous diseases and regulates the permeability of different tissues. The aim of this study is to investigate the effects of histamine on the electrophysiology ...
Resting tension affects eNOS activity in a calcium- dependent way in airways
(2007)
The alteration of resting tension (RT) from 0.5 g to 2.5 g increased significantly airway smooth muscle contractions induced by acetylcholine (ACh) in rabbit trachea. The decrease in extracellular calcium concentration ...
Epithelium-dependent effect of L-glutamate on airways: involvement of prostaglandins
(2002)
WE, investigated the effect of the excitatory amino acid (EAA) receptor agonists L-glutamate, N-methyl-D-aspartate (NMDA), (RS)-a-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) and kainic acid on KCl-induced ...