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Dose-Related Shortening of Ventricular Tachycardia Cycle Length After Administration of the K-ATP Channel Opener Bimakalim in a 4-Day-Old Chronic Infarct Anesthetized Pig Model
(2009)
Potassium channel openers are known to act on potassium ATP-dependent channels in cardiac tissue. Such agents may exacerbate acceleration of acute ischemia-induced ventricular repolarization and aggravate arrhythmias. To ...
Assessment of local atrial repolarization in a porcine acetylcholine model of atrial flutter and fibrillation
(2009)
Objectives - Progressive electrical alternans followed by conduction block and fibrillatory conduction have been suggested to precede disorganization of atrial flutter (Afl) to atrial fibrillation (AF). The purpose of the ...