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Inflammatory and oxidative stress biomarkers in allergic rhinitis: the effect of smoking
(2009)
Accumulating evidence confirms the presence of pan-airway inflammation in allergic rhinitis patients. Smoking is known to affect the asthmatic airway inflammation. However, no study has evaluated the impact of smoking on ...
Portable exhaled nitric oxide as a screening tool for asthma in young adults during pollen season
(2008)
Background: The fraction of exhaled NO (FeNO) is valuable for the follow-up of asthmatic patients. However, its usefulness as a screening tool for asthma is not established. Methods: We screened a population of 961 university ...
The acute effect of smoking in healthy and asthmatic smokers
(2010)
Background Acute exposure to cigarette smoke is related to airway and systemic inflammation and oxidative stress. Little is known about the acute effect of cigarette smoking in smoking asthmatics. The aim of this study was ...
Exhaled NO and exhaled breath condensate pH in the evaluation of asthma control
(2011)
Background: Asthma is a chronic inflammatory airways disorder. However, no biomarker of airways inflammation has been included in the assessment of asthma control. Objective: To evaluate exhaled NO (FeNO) and exhaled breath ...
Clinical, functional and biochemical changes during recovery from COPD exacerbations
(2009)
The pathways underlying chronic obstructive pulmonary disease exacerbations (ECOPD) remain unclear. This study describes the clinical., functional and biochemical changes during recovery from ECOPD. Thirty hospitalized ...
COPD prevalence and the differences between newly and previously diagnosed COPD patients in a spirometry program
(2010)
Aims: To evaluate the prevalence and severity of COPD in a primary care population participating in a spirometry program. Differences between newly and previously diagnosed COPD patients were identified. Methods: A spirometry ...
Systemic and airway inflammation and the presence of emphysema in patients with COPD
(2010)
The aim of this study was to determine the impact of HRCT-confirmed emphysema on biomarkers evaluating airway and systemic inflammation in COPD patients. Forty-nine consecutive male COPD outpatients with stable COPD were ...
Matrix Metalloproteinases in Respiratory Diseases: From Pathogenesis to Potential Clinical Implications
(2009)
Matrix metalloproteinases (MMPs) are zinc-endopeptidases responsible for degradation of the extracellular matrix (ECM) components including basement membrane collagen, interstitial collagen, fibronectin, and various ...
Nasal continuous positive airway pressure treatment reduces systemic oxidative stress in patients with severe obstructive sleep apnea syndrome
(2009)
Objective: To evaluate whether nasal continuous positive airway pressure (nCPAP) reduces oxidative stress in patients with severe obstructive sleep apnea (OSA) syndrome. Materials and methods: Forty-six patients with severe ...
VEGF, TNF-alpha and 8-isoprostane levels in exhaled breath condensate and serum of patients with lung cancer
(2009)
The aim of the present study was to evaluate the levels of VEGF, 8-isoprostane and TNF-alpha in EBC and serum of patients with primary lung cancer prior to the initiation of any treatment, in order to evaluate their possible ...