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Differential expression of hypoxia-inducible factor 1 alpha in non-small cell lung cancer and small cell lung cancer
(2012)
OBJECTIVES: The aim of this study was to compare the expression of hypoxia-inducible factor 1 alpha and vascular endothelial growth factor in small cell lung cancer and subtypes of non-small cell lung cancer and examine ...
Non-invasive ventilation in chronic hypercapnic COPD patients with exacerbation and a pH of 7.35 or higher
(2007)
Background: Current guidelines suggest the use of non-invasive ventilation (NIV) in hypercapnic chronic obstructive pulmonary disease (COPD) exacerbations in patients presenting with a pH of 7.25-7.35. The aim of this study ...
8-Isoprostane levels in serum and bronchoalveolar lavage in idiopathic pulmonary fibrosis and sarcoidosis
(2013)
Objective and design: Sarcoidosis and idiopathic pulmonary fibrosis (IPF) are both associated with deregulated inflammatory mechanisms partially triggered by aggravated oxidative stress. 8-Isoprostane has been proposed as ...
COPD prevalence and the differences between newly and previously diagnosed COPD patients in a spirometry program
(2010)
Aims: To evaluate the prevalence and severity of COPD in a primary care population participating in a spirometry program. Differences between newly and previously diagnosed COPD patients were identified. Methods: A spirometry ...
The Association of Metabolic Syndrome with Adipose Tissue Hormones and Insulin Resistance in Patients with COPD without Co-morbidities
(2011)
Chronic obstructive pulmonary disease (COPD) and metabolic syndrome represent common causes of morbidity and mortality in ageing populations. The effect of the co-existence of COPD and metabolic syndrome on adipose tissue ...
Pulmonary arterial hypertension in a patient with common variable immunodeficiency and unilateral bronchiectasis: Successful treatment with iloprost
(2007)
The present study describes a case of severe pulmonary arterial hypertension (PAH) associated with unilateral lung destruction due to bronchiectasis in a patient with common variable immunodeficiency (CVID). Initially, the ...
One-year non-invasive ventilation in chronic hypercapnic COPD: Effect on quality of life
(2008)
The data on long-term application of non-invasive ventilation (NIV) in patients with chronic respiratory failure due to COPD are contradictory. We evaluated the effect of the addition of NIV to optimal treatment for 1 year ...
Noninvasive Ventilation in Chronic Respiratory Failure: Effects on Quality of Life
(2011)
Background: Noninvasive ventilation (NIV) has been found to be an essential technique to treat chronic respiratory failure (CRF) resulting from restrictive thoracic disorders (RTD). The last decades were characterized by ...
Increased oxidative stress in exudative pleural effusions - A new marker for the differentiation between exudates and transudates?
(2005)
Study objectives: Oxidative stress has been associated with various respiratory disorders. We tested the hypothesis that exudates would present higher levels of oxidative stress compared to transudates, expressing the ...
Resting tension effect on airway smooth muscle: the involvement of epithelium
(2005)
We studied the influence of resting tension (RT) on rabbit tracheal smooth muscle (TSM) contractions induced by acetylcholine or KCl as well as the role of epithelium and the endogenously produced nitric oxide, prostanoids ...