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Anti-a actinin antibodies as new predictors of response to treatment in autoimmune hepatitis type 1
(2012)
Background We reported that combined presence of autoantibodies (Abs) against filamentous-actin (AFA) and a-actinin are specific for autoimmune hepatitis type 1 (AIH-1) diagnosis. Aim To explore our data and assess whether ...
Autoimmune hepatitis, one disease with many faces: Etiopathogenetic, clinico-laboratory and histological characteristics
(2015)
Autoimmune hepatitis (AIH) is an unresolving progressive liver disease of unknown etiology characterized by hypergammaglobulinemia, autoantibodies detection and interface hepatitis. Due to the absence of specific diagnostic ...
Antimitochondrial antibodies of immunoglobulin G3 subclass are associated with a more severe disease course in primary biliary cirrhosis
(2007)
Background/Aims: Primary biliary cirrhosis (PBC) is characterised by the presence of immunoglobulin (Ig) G antimitochondrial antibodies (AMA), which are routinely detected by indirect immunofluorescence (IFL) using composite ...
Bone marrow findings in patients with autoimmune liver diseases
(2008)
Background and Aims: We have recently reported quantitative and qualitative differences of the bone marrow (BM) hematopoietic progenitor cells in autoimmune hepatitis type-1 (AIH-1) and primary biliary cirrhosis (PBC). In ...
Anti-alpha-actinin antibodies cross-react with Anti-ssDNA antibodies in active autoimmune hepatitis
(2008)
Recently, we have observed that the association of anti-F-actin autoantibodies (Abs) with anti-alpha-actinin Abs (double reactivity) was correlated with liver disease activity in autoimmune hepatitis type 1 (AIH-1; Gueguen ...
A case of membranous nephropathy associated with Sjogren syndrome, polymyositis and autoimmune hepatitis
(2008)
Sjogren syndrome (SS) is a chronic systemic autoimmune disease characterized by lymphocylic infiltration of exocrine glands, especially lacrimal and salivary. The immunologic process which occurs in this syndrome is B cell ...
Diagnostic relevance and clinical significance of the new enhanced performance M2 (MIT3) ELISA for the detection of IgA and IgG antimitochondrial antibodies in primary biliary cirrhosis
(2007)
Background/aims: Antimitochondrial antibodies (AMAs) are the serological hallmark of primary biliary cirrhosis (PBC). We evaluated the sensitivity and specificity of a new M2 enhanced performance enzyme-linked immunosorbent ...
Prevalence of gastric parietal cell antibodies and intrinsic factor antibodies in primary biliary cirrhosis
(2010)
Background: We investigated the prevalence of antibodies against gastric parietal cells (GPA), intrinsic factor antibodies (IFA) and the presence of pernicious anemia in a large cohort of primary biliary cirrhosis (PBC) ...
IgA anti-b2GPI antibodies in patients with autoimmune liver diseases
(2008)
Introduction Recently, we reported a high prevalence of immunoglobulin G and/or immunoglobulin M anticardiolipin antibodies (aCL) in patients with autoimmune liver diseases, namely, autoimmune hepatitis (AIH), primary ...