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Hypoxia-induced changes in plasma micro-RNAs correlate with pulmonary artery pressure at high altitude
(2018)
In vitro and animal studies revealed micro-RNAs (miRs) to be involved in modulation of hypoxia-induced pulmonary hypertension (HPH). However, knowledge of circulating miRs in humans in the context of HPH is very limited. ...
A mixture of routinely encountered xenobiotics induces both redox adaptations and perturbations in blood and tissues of rats after a long-term low-dose exposure regimen: The time and dose issue
(2019)
Exposure of humans to xenobiotic mixtures is a continuous state during their everyday routine. However, the majority of toxicological studies assess the in vivo effects of individual substances rather than mixtures. ...
C-reactive protein as a potential biomarker of residual obstructive sleep apnea following adenotonsillectomy in children
(2016)
Study Objectives: Adenotonsillectomy (AT) is first-line treatment for pediatric obstructive sleep apnea (OSA), with most children having improvements in polysomnography (PSG). However, many children have residual OSA ...
Passive range of motion changes in young children with spastic diplegia. A study during the initial stages of independent walking
(2019)
PURPOSE: To investigate how the onset of independent walking in children with Cerebral Palsy (CP) influences the Passive Range of Motion (PROM) of lower limb joints. METHOD: Sixteen children with CP, GMFCS levels I and II, ...
Bone mineral density in vocational and professional ballet dancers
(2017)
Summary: According to existing literature, bone health in ballet dancers is controversial. We have verified that, compared to controls, young female and male vocational ballet dancers have lower bone mineral density (BMD) ...
Immune checkpoint inhibitor-induced musculoskeletal manifestations
(2021)
Immune checkpoint inhibitors (ICI) associate with a wide range of immune-related adverse events (Ir-AE), including musculoskeletal manifestations. We aimed at identifying all studies reporting musculoskeletal Ir-AE. An ...
Effects of controlled dehydration on sleep quality and quantity: A polysomnographic study in healthy young adults
(2019)
Dehydration is associated with several alternations in body homeostasis involving both physiological and mental aspects. In addition some studies have reported a negative effect of dehydration on subjectively assessed ...
Heart rate variability during high heat stress: A comparison between young and older adults with and without type 2 diabetes
(2016)
We examined whether older individuals with and without type 2 diabetes (T2D) experience differences in heart rate variability (HRV) during a 3-hour exposure to high heat stress compared to young adults. Young (YOUNG; n=22; ...
Progression of conventional cardiovascular risk factors and vascular disease risk in individuals: insights from the PROG-IMT consortium
(2020)
Aims: Averaged measurements, but not the progression based on multiple assessments of carotid intima-media thickness, (cIMT) are predictive of cardiovascular disease (CVD) events in individuals. Whether this is true for ...
Continuous chest compressions with asynchronous ventilation improve survival in a neonatal swine model of asphyxial cardiac arrest
(2021)
Background: Guidelines for neonatal resuscitation recommend a 3:1 compression to ventilation ratio. However, this recommendation is based on expert opinion and consensus rather than strong scientific evidence. Our primary ...