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Magnesium as a relaxing factor of airway smooth muscles
(2001)
in the search for effective treatment of a life-threatening asthma attack, intravenous magnesium infusion has been studied in asthmatic patients because of its potential effect to reverse bronchospasm and improve pulmonary ...
Naturally occurring tumor-specific CD8(+) T-cell precursors in individuals with and without cancer
(2010)
Boosting pre-existing, naturally occurring cytolytic CD8(+) T-cell (CTLs) responses directed against class-I MHC-restricted peptides of tumor antigens, represents a primary goal of cancer immunotherapy. The number of ...
Indoleamine 2,3-dioxygenase (IDO) expression in lung cancer
(2007)
Background: The expression of indoleamine 2,3-dioxygenase (IDO) by tumor cells has been considered as a major tumor immune escape mechanism. The aim of this study was to investigate the expression of IDO in lung cancer ...
Serum vascular endothelial growth factor is related to systemic oxidative stress in patients with lung cancer
(2008)
Vascular endothelial growth factor (VEGF) is known to play crucial rote in tumour angiogenesis. It is demonstrated that VEGF can be up-regulated by oxidative stress. The aim of this study was to determine the serum VEGF ...
Azithromycin has a direct relaxant effect on precontracted airway smooth muscle
(2006)
Macrolides have been proven to have beneficial bacteriostatic and anti-inflammatory properties, but very little is known about the potential value of their bronchodilatory effect. Therefore, in the present study we ...
Therapeutic value of antidepressants in asthma
(2005)
Laboratory and clinical data provide evidence that a biological linkage exists between asthma and depression. Cytokines are key molecules in both diseases. They promote allergic reaction as well as depressive symptomatology. ...
Effects of smoking cessation on serum leptin and adiponectin levels
(2015)
Background: Evidence on the association of leptin and adiponectin and smoking is limited and discordant. Leptin and adiponectin represent the most abundant adipokines in human plasma that play crucial roles in the ...
Reactive oxygen metabolites (ROMs) as an index of oxidative stress in obstructive sleep apnea patients
(2003)
STUDY OBJECTIVES: Obstructive sleep apnea syndrome (OSA) is accompanied by oxygen desaturation and arousal from sleep. Free oxygen radicals are highly reactive molecules which could be produced by the OSA phenomenon of ...
Discrimination of exudative pleural effusions based on multiple biological parameters
(2007)
Pleural effusion is a common complication of various diseases. Conventional methods are not always capable of establishing the cause of pleural effusion, so alternative tests are needed. The aim of this study was to explore ...
Serum levels of oxidative stress as a marker of disease severity in idiopathic pulmonary fibrosis
(2008)
Background: Idiopathic Pulmonary fibrosis (IPF) is a fatal illness characterized by progressive fibrosis resulting in severe dyspnea and impairment Of lung function. Although the mechanisms by which lung fibrosis develops ...