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The involvement of HER2 and p53 status in the regulation of telomerase in irradiated breast cancer cells
(2009)
Cancer cell characteristics may play a pivotal role in the response to therapy by activating or deactivating different molecular pathways. In the present study, we investigated the implication of breast cancer cell features, ...
hTERT regulation by NF-kappa B and c-myc in irradiated HER2-positive breast cancer cells
(2011)
Purpose: Telomerase activity (TA), frequently observed in cancer, compensates for telomere shortening thus preventing cell senescence and conferring resistance to therapy. In the present study, we investigated the expression ...
Survivin regulation by HER2 through NF-kappa B and c-myc in irradiated breast cancer cells
(2011)
Radiotherapy is an important treatment modality against cancer resulting in apoptosis and inhibition of cell growth. Survivin is an important cancer biomarker conferring to tumour cells increased survival potential by ...