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Parental History of Adenotonsillectomy Is Associated with Obstructive Sleep Apnea Severity in Children with Snoring

Alexopoulos, E. I.; Charitos, G.; Malakasioti, G.; Varlami, V.; Gourgoulianis, K.; Zintzaras, E.; Kaditis, A. G. (2014)

Objective To test the hypothesis that history of adenoidectomy and/or tonsillectomy (AT) in at least 1 of the parents during childhood, is a risk factor for moderate-to-severe obstructive sleep apnea (OSA) (apnea-hypopnea ...

Nocturnal enuresis is associated with moderate-to-severe obstructive sleep apnea in children with snoring

Alexopoulos, E. I.; Malakasioti, G.; Varlami, V.; Miligkos, M.; Gourgoulianis, K.; Kaditis, A. G. (2014)

BACKGROUND: Conflicting data suggest that prevalence of monosymptomatic primary nocturnal enuresis (NE) increases with increasing severity of obstructive sleep apnea (OSA) in childhood and especially in girls. We hypothesized ...

Effects Of Severity Of Sleep Apnea On Serum Lipid Levels In Greek Children With Snoring

Alexopoulos, E.; Kaditis, A.; Gletsou, E.; Varlami, V.; Kostadima, E.; Evangelopoulos, K.; Malakasioti, G.; Chaidas, K.; Ntamagka, G.; Karathanasi, A.; Gourgoulianis, K. (2010)

Effects of adenotonsillectomy on R-R interval and brain natriuretic peptide levels in children with sleep apnea: A preliminary report

Kaditis, A. G.; Chaidas, K.; Alexopoulos, E. I.; Varlami, V.; Malakasioti, G.; Gourgoulianis, K. (2011)

Objectives: Obstructive sleep apnea is associated with decreased R-R interval length and overall R-R interval variability in the electrocardiogram along with increased morning brain natriuretic peptide (BNP) blood levels. ...

Low Morning Serum Cortisol Levels in Children with Tonsillar Hypertrophy and Moderate-to-Severe OSA

Malakasioti, G.; Alexopoulos, E. I.; Varlami, V.; Chaidas, K.; Liakos, N.; Gourgoulianis, K.; Kaditis, A. G. (2013)

Background: Hypertrophic tonsillar tissue in children with obstructive sleep apnea (OSA) has enhanced expression of glucocorticoid receptors, which may reflect low endogenous cortisol levels. We have evaluated the effect ...

Correlation of Urinary Excretion of Sodium With Severity of Sleep-Disordered Breathing in Children: A Preliminary Study

Kaditis, A. G.; Alexopoulos, E. I.; Evangelopoulos, K.; Kostadima, E.; Varlami, V.; Boultadakis, E.; Liakos, N.; Zakynthinos, E.; Zintzaras, E.; Gourgoulianis, K. (2010)

Background: Nocturnal urinary sodium excretion is related to blood pressure (BP) levels. Elevated BP and increased nocturnal natriuresis have been demonstrated in adults with sleep apnea. Although evidence indicates increased ...

Low-grade albuminuria in children with obstructive sleep apnea

Varlami, V.; Malakasioti, G.; Alexopoulos, E. I.; Theologi, V.; Theophanous, E.; Liakos, N.; Daskalopoulou, E.; Gourgoulianis, K.; Kaditis, A. G. (2013)

Small urinary protein loss (low-grade albuminuria or microalbuminuria) may reflect altered permeability of the glomerular filtration barrier. In the present study, it was hypothesized that children with obstructive sleep ...

Uric acid excretion in North American and Southeast European children with obstructive sleep apnea

Kaditis, A.; Gozal, D.; Snow, A. B.; Kheirandish-Gozal, L.; Alexopoulos, E.; Varlami, V.; Papathanasiou, A. A.; Capdevila, O. S.; Bhattacharjee, R.; Kim, J.; Gourgoulianis, K.; Zintzaras, E. (2010)

Background and objectives: Responses to nocturnal hypoxemia accompanying sleep-disordered breathing (SDB) may vary in different populations. Aims of this study were to (1) assess whether severity of SDB is related to uric ...

Oxidative stress and inflammatory markers in the exhaled breath condensate of children with OSA

Malakasioti, G.; Alexopoulos, E.; Befani, C.; Tanou, K.; Varlami, V.; Ziogas, D.; Liakos, P.; Gourgoulianis, K.; Kaditis, A. G. (2012)

Obstructive sleep apnea (OSA) in children has been associated with systemic inflammation and oxidative stress. Limited evidence indicates that pediatric OSA is associated with oxidative stress and inflammation in the airway. ...