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DNA damage and repair efficiency in lymphocytes from schizophrenic patients
(2004)
In the present study we examined schizophrenic patients' lymphocytes sensitivity to the effects of external factors, such as hydrogen peroxide and gamma-irradiation and also their repair efficiency with the comet assay. ...
Duplex Real-time PCR assay and SYBR green I melting curve analysis for molecular identification of HPV genotypes 16, 18, 31, 35, 51 and 66
(2015)
Long-term infection with high-risk HPV genotypes is the leading cause of cervical cancer. In the present study a Duplex Real-time PCR assay was developed in order to identify HPV types 16, 18, 31, 35, 51 and 66 in three ...
Alterations of Deadenylase Expression in Acute Leukemias: Evidence for Poly(A)-Specific Ribonuclease as a Potential Biomarker
(2012)
Background/Aims: The degradation of mRNA is a key process in the control of gene expression correlated to anomalous cell proliferation. The rate-limiting step of mRNA degradation is the removal of the poly(A) tail by ...
Geographic variations of human papilloma virus infection and their possible impact on the effectiveness of the vaccination programme
(2008)
Greece is one of the first countries of the European Union to introduce a human. papilloma virus (HPV) vaccine in its national vaccination programme. Geographical variations in the prevalence of the different HPV types ...
Association of allelic loss at the FHIT locus and p53 alterations with tumour kinetics and chromosomal instability in non-small cell lung carcinomas (NSCLCs)
(2001)
The FHIT gene, located at the FRA3B fragile site of chromosome 3p14.2, encodes a 16.8 kD homologue of the yeast enzyme diadenosine tetraphosphate (Ap(4)A) hydrolase, Frequent allelic losses at this region in various ...
Practical approaches to effective management of intestinal radiation injury: Benefit of resectional surgery
(2011)
AIM: To study the outcome of patients undergoing surgical resection of the bowel for sustained radiation-induced damage intractable to conservative management. METHODS: During a 7-year period we operated on 17 cases (5 ...
Efficacy of low dose temozolomide in combination with bortezomib in U87 glioma cells: a flow cytometric analysis
(2015)
Introduction: Maximizing responses of malignant gliomas is hampered by resistance to temozolomide (TMZ). Increasing efficacy but not toxicity is a key issue when testing drug combinations. The antimyeloma agent bortezomib ...
Molecular Cloning, Carbohydrate Specificity and the Crystal Structure of Two Sclerotium rolfsii Lectin Variants
(2015)
SRL is a cell wall associated developmental-stage specific lectin secreted by Sclerotium rolfsii, a soil-born pathogenic fungus. SRL displays specificity for TF antigen (Gal13GalNAc--Ser//Thr) expressed in all cancer types ...
A new role of PET/CT for target delineation for radiotherapy treatment planning for head and neck carcinomas
(2012)
Fluorine-18-fluorodeoxyglucose- positron emission tomography (F-18-FDG PET) in head and neck cancer patients is useful for staging, identification of macroscopic disease, detection of invaded lymph nodes and distant ...
Sequence variation analysis of the E2 gene of human papilloma virus type 16 in cervical lesions from women in Greece
(2012)
The E2 gene of human papilloma virus is expressed at the early stage of the viral life cycle, encoding the E2 transcription factor, and regulates the expression of E6 and E7 oncogenes. Disruption of E2 gene due to viral ...