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Different patterns of p16 immunoreactivity in cervical biopsies: correlation to lesion grade and HPV detection, with a review of the literature

Kostopoulou, E.; Samara, M.; Kollia, P.; Zacharouli, K.; Mademtzis, I.; Daponte, A.; Messinis, I. E.; Koukoulis, G. (2011)

p16 is one extensively studied marker in gynecological pathology. However, its routine application in the diagnosis of squamous intraepithelial lesions of the uterine cervix may present difficulties for the general ...

Correlation Between Cyclin B1 Immunostaining in Cervical Biopsies and HPV Detection by PCR

Kostopoulou, E.; Samara, M.; Kollia, P.; Zacharouli, K.; Mademtzis, I.; Daponte, A.; Messinis, I. E.; Koukoulis, G. (2009)

In recent years, experimental data on the roles of viruses and cyclin B1 in G2/M arrest has accumulated. The aim of our study Was to immunohistochemically examine a series of cervical squamous intraepithelial lesions for ...

Xanthogranulomatous salpingitis: Report of three cases and comparison with a case of pseudoxanthomatous salpingitis

Kostopoulou, E.; Daponte, A.; Kallitsaris, A.; Papamichali, R.; Kalodimos, G.; Messinis, I. E.; Koukoulis, G. (2008)

Xanthogranulomatous inflammation, an uncommon form of chronic inflammation, has been described in several organs including those of the female genital tract. A rare condition described as pseudoxanthomatous salpingitis or ...

Prognostic significance of Hypoxia-Inducible Factor 1 alpha(HIF-1alpha) expression in serous ovarian cancer: an immunohistochemical study

Daponte, A.; Ioannou, M.; Mylonis, I.; Simos, G.; Minas, M.; Messinis, I. E.; Koukoulis, G. (2008)

Background: The hypoxia-inducible factor (HIF) has emerged as an attractive target for cancer therapy. The few publications addressing the prognostic significance of Hypoxia-Inducible Factor 1 alpha (HIF-1 alpha) cellular ...

Retinoid receptor alpha and beta expression in serous ovarian tumors

Daponte, A.; Kostopoulou, E.; Chiotoglou, I.; Vanakara, P.; Minas, M.; Nakou, M.; Kallitsaris, A.; Kollia, P.; Koukoulis, G.; Messinis, I. E. (2007)

The expression of retinoid acid receptors alpha (RAR alpha) and beta (RAR beta) and estrogen receptor alpha (ER alpha) was assessed by immunohistochemistry and Western blotting in normal ovaries, serous cystadenoma (n = ...