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Acute phase markers for the differentiation of infectious and malignant pleural effusions
(2007)
Acute-phase markers, such as C-reactive protein (CRP), interleukin-6 (IL-6) and tumor necrosis factor alpha (TNF-α), have been studied in inflammatory and malignant disorders. We examined the diagnostic value of these ...
Endothelial Progenitor Cells in the Pathogenesis of Idiopathic Pulmonary Fibrosis: An Evolving Concept
(2013)
Background: Idiopathic pulmonary fibrosis (IPF) has been associated with abnormal vascular remodeling. Bone marrow derived endothelial progenitor cells (EPCs) are considered to possess lung tissue repair and vascular ...
8-Isoprostane levels in serum and bronchoalveolar lavage in idiopathic pulmonary fibrosis and sarcoidosis
(2013)
Objective and design: Sarcoidosis and idiopathic pulmonary fibrosis (IPF) are both associated with deregulated inflammatory mechanisms partially triggered by aggravated oxidative stress. 8-Isoprostane has been proposed as ...
Pleural fluid protein is inversely correlated with age in uncomplicated parapneumonic pleural effusions
(2013)
Objectives: Assess whether age influences standard biochemical parameters used in the differential diagnosis of transudative and exudative pleural effusions. Design and methods: We retrospectively analyzed data from the ...
The DJ-1 protein as a candidate biomarker in obstructive sleep apnea syndrome
(2014)
Oxidative stress has a central role in the pathophysiology of obstructive sleep apnea syndrome (OSAS). The DJ-1 protein functions as a sensor of oxidative stress, acting both as a reactive oxygen species scavenger (ROS) ...
The acute effect of smoking in healthy and asthmatic smokers
(2010)
Background Acute exposure to cigarette smoke is related to airway and systemic inflammation and oxidative stress. Little is known about the acute effect of cigarette smoking in smoking asthmatics. The aim of this study was ...
Diagnostic accuracy of biomarkers of oxidative stress in parapneumonic pleural effusions
(2011)
P>Background The imbalance between oxidants and antioxidants is referred to as oxidative stress and has been associated with various respiratory disorders. The aim of this study was the assessment of 8-isoprostane (8-iso-PGF(2 ...
Systemic and airway inflammation and the presence of emphysema in patients with COPD
(2010)
The aim of this study was to determine the impact of HRCT-confirmed emphysema on biomarkers evaluating airway and systemic inflammation in COPD patients. Forty-nine consecutive male COPD outpatients with stable COPD were ...
Matrix Metalloproteinase Levels in the Differentiation of Parapneumonic Pleural Effusions
(2010)
Background: Matrix metalloproteinases (MMPs) have been implicated in the escalation of fibrosis and remodeling which are central to the subsequent progression of a parapneumonic pleural effusion to empyema. Objectives: The ...
Interleukin-27 improves the ability of adenosine deaminase to rule out tuberculous pleural effusion regardless of pleural tuberculosis prevalence
(2015)
Background: Interleukin-27 (IL-27) has been proposed to be useful for diagnosing tuberculous pleural effusion (TPE). Adenosine deaminase (ADA) has been long used for the same purpose. The aim of this study was to compare ...