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Best practice in the management of storage symptoms in male lower urinary tract symptoms: a review of the evidence base
(2018)
Storage lower urinary tract symptoms (LUTS) are characterized by an altered bladder sensation, increased daytime frequency, nocturia, urgency and urgency incontinence. Some evidence underlines the role of metabolic factors, ...
IDO decreases glycolysis and glutaminolysis by activating GCN2K, while it increases fatty acid oxidation by activating AhR, thus preserving CD4+ T-cell survival and proliferation
(2018)
It is generally hypothesized in the literature that indoleamine 2,3-dioxygenase (IDO), by degrading L-tryptophan along the kynurenine pathway, suppresses CD4+ T-cell function by inducing apoptosis, inhibiting proliferation ...
The dissipation and microbial ecotoxicity of tebuconazole and its transformation products in soil under standard laboratory and simulated winter conditions
(2018)
Tebuconazole (TBZ) is a widely used triazole fungicide at EU level on cereals and vines. It is relatively persistent in soil where it is transformed to various transformation products (TPs) which might be environmentally ...
Is irisin the new player in exercise-induced adaptations or not? A 2017 update
(2018)
Irisin is produced by a proteolytic cleavage of fibronectin type III domain-containing protein 5 (FNDC5) and has emerged as a potential mediator of exercise-induced energy metabolism. The purpose of this study was to review ...
Exploring the potential of mucin 13 (MUC13) as a biomarker for carcinomas and other diseases
(2018)
Mucin 13 (MUC13) is a cell surface glycoprotein aberrantly expressed in a variety of epithelial carcinomas. Thus far, the role of MUC13 in various diseases remains elusive. To the best of our knowledge, this is the first ...
Reproducibility of apparent diffusion coefficient measurements evaluated with different workstations
(2018)
Aim To evaluate apparent diffusion coefficient (ADC) measurements of breast lesions on different computer platforms to address post-processing influences on ADC measurement reproducibility. Materials and methods One hundred ...
Uric acid increases cellular and humoral alloimmunity in primary human peripheral blood mononuclear cells
(2018)
Aim: Hyperuricaemia is common among kidney transplant recipients and has been associated with worse graft outcome. Since episodes of acute cellular rejection and chronic humoral rejection contribute to decreased graft ...
Checkpoint modulation in chronic hepatitis B: From hypothesis to approval
(2018)
[No abstract available]
Measuring performance on the Healthcare Access and Quality Index for 195 countries and territories and selected subnational locations: A systematic analysis from the Global Burden of Disease Study 2016
(2018)
Background A key component of achieving universal health coverage is ensuring that all populations have access to quality health care. Examining where gains have occurred or progress has faltered across and within countries ...
A chronic alcoholic man with high fever, neck rigidity and loss of consciousness: Remember the Austrian syndrome a commonly unrecognised invasive pneumococcus triad
(2018)
Austrian syndrome is a rare medical condition characterised by the triad of pneumonia, meningitis and endocarditis due to Streptococcus pneumoniae. Native aortic valve insufficiency is the most common cause of cardiac ...