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Association Between the Interleukin-1 beta Gene (IL1B) C-511T Polymorphism and the Risk of Diabetic Nephropathy in Type 2 Diabetes: A Candidate-Gene Association Study
(2014)
Variants of the interleukin-1 beta gene (IL1B) are implicated in the development of diabetic nephropathy (DN). The present candidate-gene association study was conducted to investigate the association between the IL1B ...
Network Analysis of Randomized Controlled Trials in Multiple Sclerosis
(2012)
Background: The optimal treatment of multiple sclerosis (MS) is not yet well-defined. Objective: To estimate the relative effectiveness of treatments in MS, we performed a network of multiple-treatments meta-analysis of ...
Randomized Trials of Dopamine Agonists in Restless Legs Syndrome: A Systematic Review, Quality Assessment, and Meta-Analysis
(2010)
Background: The use of dopamine agonists (DAs) for the treatment of restless legs syndrome (RLS) has been assessed in numerous randomized clinical trials (RCTs). Objectives: The aims of this study were to assess the reporting ...
Evidence of an association between the scavenger receptor class B member 2 gene and Parkinson's disease
(2012)
Lysosomal protein 2 (LIMP2), the product of the scavenger receptor class B member 2 (SCARB2) gene, is a ubiquitously expressed transmembrane protein that is the mannose-6-phosphateindependent receptor for glucocerebrosidase ...
Assessment of the Relative Effectiveness and Tolerability of Treatments of Type 2 Diabetes Mellitus: A Network Meta-analysis
(2014)
Purpose: The relative effectiveness and tolerability of treatments for type 2 diabetes mellitus (T2DM) is not well understood because few randomized, controlled trials (RCTs) have compared these treatments directly. The ...
Restless legs syndrome in hemodialysis patients: an epidemiologic survey in Greece
(2013)
Background: Restless legs syndrome (RLS) is a sensorimotor disorder characterized by an uncontrolled need to move extremities accompanied by unpleasant sensations, which frequently leads to sleep disturbances. In hemodialysis ...
A network meta-analysis of randomized controlled trials for comparing the effectiveness and safety profile of treatments with marketing authorization for relapsing multiple sclerosis
(2013)
What is known and objectiveThe relative effectiveness and safety profile of the treatments with marketing authorization for relapsing multiple sclerosis (MS) are not well known because randomized controlled trials with ...
Restless legs syndrome does not affect 3-year mortality in hemodialysis patients
(2015)
Objective: Uremic restless legs syndrome (RLS) has been related to an enhanced mortality of hemodialysis (HD) patients. In the general population studies of this association have yielded inconsistent results. The aim of ...