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Crohn's disease-specific anti-CUZD1 pancreatic antibodies are absent in ruminants with paratuberculosis
(2015)
Background: Pancreatic autoantibodies (PABs) specifically recognizing GP2 and/or CUZD1 are present in more than 35% of patients with Crohn's disease (CrD). We have recently provided evidence of the presence of GP2-specific ...
Urinary tract infection as a risk factor for autoimmune liver disease: From bench to bedside
(2012)
Autoimmune liver diseases include autoimmune hepatitis (AIH), primary biliary cirrhosis (PBC), and primary sclerosing cholangitis. A variety of environmental and genetic risk factors have been associated with these conditions. ...
Vitamin D in autoimmune liver disease
(2013)
The development of autoimmune disease is based on the interaction of genetic susceptibility and environmental causes. Environmental factors include infectious and noninfectious agents, with some of these factors being ...
Familial primary biliary cirrhosis: Like mother, like daughter?
(2012)
The reasons underlying why autoimmune diseases overwhelmingly affect women more than men are not clear. Nor are the reasons why autoimmune disease is more prevalent in families. This review uses primary biliary cirrhosis ...
Peculiar antibody reactivity to human connexin 37 and its microbial mimics in patients with Crohn's disease
(2011)
Background/aims: We found that pooled Crohn's disease (CD) sera strongly react with a human gap-junction connexin 37 (Cx37) peptide and tested for anti-Cx37 antibody reactivity in sera from CD patients and controls. We ...
Helicobacter pylori and autoimmune disease: Cause or bystander
(2014)
Helicobacter pylori (H. pylori) is the main cause of chronic gastritis and a major risk factor for gastric cancer. This pathogen has also been considered a potential trigger of gastric autoimmunity, and in particular of ...
Diagnostic and clinical significance of anti-centromere antibodies in primary biliary cirrhosis
(2013)
Primary biliary cirrhosis (PBC) is an autoimmune disease of the liver characterised by biochemical evidence of cholestasis, elevated alkaline phosphatase levels and the presence of the highly disease specific anti-mitochondrial ...