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Autoimmunity and Environment: Am I at risk?
(2012)
The complex interplay between environmental factors and genetic susceptibility plays an essential role in disease pathogenesis. This is especially true for autoimmunity, where clinical reports, genomic and epidemiological ...
Peculiar antibody reactivity to human connexin 37 and its microbial mimics in patients with Crohn's disease
(2011)
Background/aims: We found that pooled Crohn's disease (CD) sera strongly react with a human gap-junction connexin 37 (Cx37) peptide and tested for anti-Cx37 antibody reactivity in sera from CD patients and controls. We ...
PBC triggers in water reservoirs, coal mining areas and waste disposal sites: From Newcastle to New York
(2010)
Various environmental factors have been proposed as triggers of primary biliary cirrhosis (PBC), a progressive autoimmune cholestatic liver disease which is characterised by the destruction of the small intrahepatic bile ...