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Albumin possesses intrinsic enolase activity towards dihydrotestosterone which can differentiate benign from malignant breast tumors
(1999)
Serum albumin was found to possess enolase activity towards the dihydrotestesterone (DHT) molecule, converting it from its 3-keto to 3-enol form. This activity was accompanied by albumin during all stages of purification, ...
Nonlinear binding of sex steroids to albumin and sex hormone binding globulin
(1997)
We have studied the binding of sex steroids to albumin and sex hormone binding globulin (SHBG) using gel filtration chromatography for the separation of the bound from the free fraction of the steroid. It was found that ...
Chemopreventive activity of very low dose dietary tannic acid administration in hepatoma bearing C3H male mice
(1999)
Tannins are plant polyphenols comprising a heterogeneous group of compounds. Tannic acid is a common tannin found in tea, coffee, immature fruits, etc. and it has also been used as a food additive. An increasing body of ...
Enzymatic conversion of dihydrotestosterone from 3-keto to 3-enol form in the rat prostate
(1996)
Dihydrotestosterone (DHT) is the active androgen, as well as a strong tumor promoter in the prostate, where several enzymes are essential for the regulation of its activity. We localized four enzymes promoting the enolization ...
Sex-hormone binding globulin from sheep serum: purification and effects of pregnancy and treatment with exogenous estradiol
(1999)
Sex-hormone binding globulin (SHBG) is a protein that binds sex steroids in the serum of many species. SHBG binds androgens and estrogens in humans and primates with high affinity, but behaves as an androgen binding protein ...
CHARACTERIZATION OF THE PROTEIN PROTECTING RNA FROM ACID PRECIPITATION AND ITS EVALUATION AS TUMOR-MARKER IN GASTROINTESTINAL AND GYNECOLOGICAL CANCER
(1995)
In a previous study, we observed increased protective activity against acid precipitation of poly (U) in the serum of tumor bearing mice and hepatoma patients. In the present study we purified and partially characterized ...
Ribonucleases protect RNA from acid precipitation
(1997)
Four, widely used, ribonucleases were found to protect their substrates from acid precipitation by causing, evidently, a modification of their physicochemical properties. The protection was dependent on the kind of substrate ...