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Dichloroacetate at therapeutic concentration alters glucose metabolism and induces regulatory t-cell differentiation in alloreactive human lymphocytes
(2013)
Background: Most cancer cells rely on aerobic glycolysis. Dichloroacetate (DCA) inhibits aerobic glycolysis and is a promising relatively nontoxic anticancer compound. However, rapidly proliferating effector T-cells also ...
Vascularized compared with nonvascularized fibular grafting for the treatment of osteonecrosis of the femoral head
(2003)
Background: We are not aware of any clinical studies in the literature comparing the results of vascularized and non- vascularized fibular grafting for the treatment of osteonecrosis of the femoral head. The purpose of ...
Diagnostic accuracy of a new clinical test (The Thessaly test) for early detection of meniscal tears
(2005)
Background: Clinical tests used for the detection of meniscal tears in the knee do not present acceptable diagnostic sensitivity and specificity values. Diagnostic accuracy is improved by arthroscopic evaluation or magnetic ...
Investigation of physicians' attitudes concerning the implementation of international classification systems of diseases as a precondition for evidence-based policy making
(2013)
This study investigated the main factors affecting physicians' attitudes toward the implementation of international classification systems of diseases. A cross-sectional study was carried out during September 2010. The ...
Gross calcification of the small bowel in a continuous ambulatory peritoneal dialysis patient with sclerosing peritonitis
(2006)
We present here the case of a continuous ambulatory peritoneal dialysis (CAPD) patient who developed sclerosing calcifying peritonitis with gross macroscopic calcification of the small bowel, a rare and life-threatening ...
Systems biology-based analysis implicates a novel role for vitamin D metabolism in the pathogenesis of age-related macular degeneration
(2011)
Vitamin D has been shown to have anti-angiogenic properties and to play a protective role in several types of cancer, including breast, prostate and cutaneous melanoma. Similarly, vitamin D levels have been shown to be ...
Characteristics of Farm Injuries in Greece
(2003)
Methodology: During a five-year period (1996-2000), 4,326 unintentional farm injuries have been recorded by the Emergency Department Injury Surveillance System in Greece. Data concerning demographic variables, accident ...
Clinical significance of organ- and non-organ-specific autoantibodies on the response to anti-viral treatment of patients with chronic hepatitis C
(2006)
Background: Development of organ- and non-organ-specific autoantibodies has been reported in hepatitis C virus patients treated with interferon-α plus/minus ribavirin. Aims: To address whether prevalence and the titre of ...
Clinical phenotype in patients with α-synuclein Parkinson's disease living in Greece in comparison with patients with sporadic Parkinson's disease
(2001)
Objective - An Ala53Thr mutation of the α-synuclein gene has been recently identified as a rare cause of autosomal Parkinson's disease (PD). The clinical characteristics of 15 patients with PD living in Greece with the ...
Enteroviral infection in Greek AIDS patients
(2004)
Objective: Prolonged intestinal replication of polioviruses has not previously been studied in Greek AIDS patients. The objective of our study was to estimate the prevalence of enteroviral infections in this population. ...