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Effects of melatonin on proliferation of cancer cell lines
(1998)
The pineal hormone melatonin has been reported to have in vitro antiproliferative effects on estrogen receptor-positive human breast cancer cell lines at concentrations near to plasma physiological concentrations (1 x ...
Lipid peroxidation and tissue damage
(1999)
In recent years it has become apparent that the oxidation of lipids, or lipid peroxidation, is a crucial step in the pathogenesis of several disease states in adult and infant patients. Lipid peroxidation is a process ...
ROS-major mediators of extracellular matrix remodeling during tumor progression
(2013)
Extracellular matrices (ECMs) represent a complex network of proteins, proteoglycans and glycosaminoglycans (GAGs), composed of independent structural domains, ultimately constituting the cell microenvironment. As a highly ...
Novel conformationally constrained pyrazole derivatives as potential anti-cancer agents
(2015)
The synthesis of 17 novel conformationally constrained pyrazole derivatives is reported herein, along with the assessment of their anti-proliferative and anti-angiogenic activities. The evaluation of their inhibitory effect ...
The Antioxidant Effects of a Polyphenol-Rich Grape Pomace Extract In Vitro Do Not Correspond In Vivo Using Exercise as an Oxidant Stimulus
(2012)
Fruits, such as grapes, are essential food of the Mediterranean diet. Grape extracts have potent antioxidant and chemopreventive properties in vitro. Numerous studies have examined the effects of plant extract administration ...
Effect of a special carbohydrate-protein bar and tomato juice supplementation on oxidative stress markers and vascular endothelial dynamics in ultra-marathon runners
(2014)
It is well established that exercise induces excessive production of reactive species leading to oxidative stress, which has been implicated in oxidative damage of macromolecules, immune dysfunction, muscle damage and ...
Oxidative stress, inflammation and angiogenesis markers in elite female water polo athletes throughout a season
(2013)
Elite athletes undergo heavy training programs throughout the year. The aim of the present study was to evaluate blood biomarkers of redox status, oxidative stress, inflammation and angiogenesis over the course of a ...