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Urate crystals induce NLRP3 inflammasome-dependent IL-1β secretion and proliferation in isolated primary human T-cells
(2015)
Background: Urate through NOD-like receptor family, pyrin domain containing 3 (NLRP3) inflammasome-dependent caspase-1 activation stimulates macrophages to secrete inteleukin-1β (IL-1β). Urate also enhances adaptive immunity ...
Hypospadias in offspring is associated with chronic exposure of parents to organophosphate and organochlorine pesticides
(2014)
We have currently evaluated the possible association between hypospadias and exposure to organophosphorus (OP) and organochlorine (OC) pesticides. For this purpose, we measured the dialkyl phosphate metabolites of ...
Hepatocellular carcinoma risk in HBeAg-negative chronic hepatitis B patients with or without cirrhosis treated with entecavir: HepNet.Greece cohort
(2015)
Hepatocellular carcinoma (HCC) may still develop in chronic hepatitis B (CHB) patients treated with lamivudine. Whether HCC rates are comparable in patients treated with the current first-line antivirals remains uncertain. ...
Normal menstrual cycle steroid hormones variation does not affect the blood levels of total adiponectin and its multimer forms
(2015)
Objective Plasma total adiponectin reveals a sexual dimorphism indicating that gonadal steroids may be involved in its secretion and/or metabolism. However, results from previous reports are conflicting and data regarding ...
Strokes and TIAs during and after Carotid Artery Doppler: Cause or Coincidence?
(2015)
The aim of the present study was to explore the prevalence of acute cerebrovascular symptoms temporally related to carotid Doppler examination (DEx), in order to increase the awareness and recording of such events and to ...
Effect of external classroom noise on schoolchildren's reading and mathematics performance: Correlation of noise levels and gender
(2015)
The present study investigated the effect of low, medium, and high traffic road noise as well as irrelevant background speech noise on primary school children's reading and mathematical performance. A total of 676 participants ...
Prospective evaluation of PBC-specific health-related quality of life questionnaires in patients with primary sclerosing cholangitis
(2015)
Background & Aims: Primary biliary cirrhosis and Primary sclerosing cholangitis are autoimmune cholestatic liver diseases sharing a lot in common, including a significant impairment of patients' health-related quality of ...
Re-imagining the museum through "touch": Reflections of individuals with visual disability on their experience of museum-visiting in Greece
(2015)
The research aim of the present study was to investigate theexperiences of individuals with visual disability regarding theirvisits to museums. To obtain relevant information, semi-structuredinterviews were conducted with ...
Malate dehydrogenase-2 inhibitor LW6 promotes metabolic adaptations and reduces proliferation and apoptosis in activated human T-cells
(2015)
Activated T cells rely on aerobic glycolysis and glutaminolysis in order to proliferate and differentiate into effector cells. Therefore, intervention in these metabolic pathways inhibits proliferation. The aim of the ...
RhBMP-7 for the Treatment of nonunion of fractures of long bones
(2015)
We report the outcome of 84 nonunions involving long bones which were treated with rhBMP-7, in 84 patients (60 men: 24 women) with a mean age 46 years (18 to 81) between 2003 and 2011. The patients had undergone a mean of ...