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Early bacterial identification among intubated patients with COVID-19 or influenza pneumonia: A european multicenter comparative clinical trial
(2021)
Rationale: Early empirical antimicrobial treatment is frequently prescribed to critically ill patients with coronavirus disease (COVID-19) based on Surviving Sepsis Campaign guidelines. Objectives: We aimed to determine ...
Severe traumatic brain injury (Tbi) – a seven-year comparative study in a department of forensic medicine
(2020)
Deaths caused by traumatic brain injury (TBI) increase in incidence every year worldwidely, mainly in developing countries. Thus, World Health Organization (WHO) estimates that in 2020, TBI will become the third main cause ...
Lack of an association between SCFD1 rs10139154 polymorphism and amyotrophic lateral sclerosis
(2022)
Amyotrophic lateral sclerosis (AL S) is a progressive neurodegenerative disease. Through a genome-wide association study (GWAS), the Sec1 family domain-containing protein 1 (SCFD1) rs10139154 variant at 14q12 has emerged ...
Enhanced expression of miR-21 and miR-150 is a feature of anti-mitochondrial antibody-negative primary biliary cholangitis
(2020)
Background & Aims: Anti-mitochondrial-autoantibodies (AMA) remain a hallmark of Primary Biliary Cholangitis (PBC) however approximately 10% of patients test negative for these antibodies. They do not differ in terms of ...
Hypoxia-Inducible Factor-2-Altered Urothelial Carcinoma: Clinical and Genomic Features
(2022)
Background: Hypoxia is recognized as a key feature of cancer growth and is involved in various cellular processes, including proliferation, angiogenesis, and immune surveillance. Besides hypoxia-inducible factor 1-alpha ...
Patterns of 1,748 Unique Human Alloimmune Responses Seen by Simple Machine Learning Algorithms
(2020)
Allele specific antibody response against the polymorphic system of HLA is the allogeneic response marker determining the immunological risk for graft acceptance before and after organ transplantation and therefore routinely ...
Differences in Mental Health and Bullying Victimization Experiences between Youth of Different Sexualities: A Bayesian Perspective
(2022)
Researchers have extensively investigated the differences in mental health and bullying victimization experiences of adolescents of different sexualities. Prior research has typically sought differences between heterosexual ...
High-tidal-volume mechanical ventilation and lung inflammation in intensive care patients with normal lungs
(2020)
Background This study was conducted to investigate whether high-tidal-volume mechanical ventilation is associated with increased lung inflammation compared with low-tidal-volume mechanical ventilation in critically ill ...
Dietary restraint is associated with adiposity and repeated attempts of food avoidance since early adolescence
(2020)
Body composition and fat distribution are predictors of health and are largely affected by eating behavior. The current study aimed to explore the adoption of dietary restraint since early adolescence, its relationship ...
Experiences of workers with disabilities receiving supported employment services in Greece
(2021)
People with disabilities (PwDs) are under-represented in the workforce, especially during times of economic recession. Supported employment is recognized as an effective practice for promoting work inclusion of PwDs, ...