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GC-MS analysis of blood for the metabonomic investigation of the effects of physical exercise and allopurinol administration on rats
(2014)
Exhaustive exercise is a generator of free radicals and reactive species in mammals. Allopurinol is a known inhibitor of xanthine oxidase, a source of free radicals during exercise. In this study, the influence of allopurinol ...
Alzheimer's disease treated patients showed different patterns for oxidative stress and inflammation markers
(2013)
Alzheimer's disease (AD) is the most common type of dementia accounting for 60-80% of the reported cases. The aim of this study was to evaluate levels of certain parameters of oxidative stress and markers of endothelial ...
Cardiotoxicity in rabbits after a low-level exposure to diazinon, propoxur, and chlorpyrifos
(2014)
Lethal cardiac complications leading to death and various arrhythmias have been reported after organophosphate and/or carbamate poisonings. The present study focuses on the long-term effects of repeated low-level exposure ...
Application of a new oxidation-reduction potential assessment method in strenuous exercise-induced oxidative stress
(2015)
Objectives: The aim of the study was to test a novel method for assessing oxidative stress, the RedoxSYS (TM) diagnostic system, a holistic, fast, minimally invasive, and requiring small sample volume method, that measures ...
Assessment of Eccentric Exercise-Induced Oxidative Stress Using Oxidation-Reduction Potential Markers
(2015)
The aim of the present study was to investigate the use of static (sORP) and capacity ORP (cORP) oxidation-reduction potential markers as measured by the RedoxSYS Diagnostic System in plasma, for assessing eccentric ...
Correlation of total polyphenolic content with antioxidant and antibacterial activity of 24 extracts from Greek domestic Lamiaceae species
(2012)
Lamiaceae family species are considered important because of their use in folk medicine, culinary and flavouring throughout the world. Their interesting bioactivities are attributed mainly to essential oils, polyphenols ...
ROS-major mediators of extracellular matrix remodeling during tumor progression
(2013)
Extracellular matrices (ECMs) represent a complex network of proteins, proteoglycans and glycosaminoglycans (GAGs), composed of independent structural domains, ultimately constituting the cell microenvironment. As a highly ...
Novel conformationally constrained pyrazole derivatives as potential anti-cancer agents
(2015)
The synthesis of 17 novel conformationally constrained pyrazole derivatives is reported herein, along with the assessment of their anti-proliferative and anti-angiogenic activities. The evaluation of their inhibitory effect ...
The Antioxidant Effects of a Polyphenol-Rich Grape Pomace Extract In Vitro Do Not Correspond In Vivo Using Exercise as an Oxidant Stimulus
(2012)
Fruits, such as grapes, are essential food of the Mediterranean diet. Grape extracts have potent antioxidant and chemopreventive properties in vitro. Numerous studies have examined the effects of plant extract administration ...