Listar por autor "Speletas, M."
Mostrando ítems 1-20 de 61
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Absence of aprataxin gene mutations in a Greek cohort with sporadic early onset ataxia and normal GAA triplets in frataxin gene
Daiou, C.; Christodoulou, K.; Xiromerisiou, G.; Panas, M.; Dardiotis, E.; Kladi, A.; Speletas, M.; Ntaios, G.; Papadimitriou, A.; Germenis, A.; Hadjigeorgiou, G. M. (2010)Phenotype of patients with the aprataxin gene mutation varies and according to previous studies, screening of aprataxin gene could be useful, once frataxin gene mutation is excluded in patients with normal GAA expansion ... -
Analysis of SLC40A1 gene at the mRNA level reveals rapidly the causative mutations in patients with hereditary hemochromatosis type IV
Speletas, M.; Kioumi, A.; LouleS, G.; Hytiroglou, P.; Tsitouridis, J.; Christakis, J.; GermeniS, A. E. (2008)Mutations in the SLC40Al gene result in a dominant genetic disorder [ferroportin disease; hereditary hemochromatosis type (HH) IV], characterized by iron overload with two different clinical manifestations, normal transferrin ... -
Analysis of SLC40A1 gene at the mRNA level reveals rapidly the causative mutations in patients with hereditary hemochromatosis type IV (vol 40, pg 353, 2008)
Speletas, M.; Kioumi, A.; Loules, G.; Hytiroglou, P.; Tsitouridis, J.; Christakis, J.; Germenis, A. E. (2013) -
Analysis of SLC40A1(Ferroportin 1) gene at mrna level reveals rapidly the causative mutations in patients with hereditary hemochromatosis type IV
Speletas, M.; Kioumi, A.; Loules, G.; Kalala, F.; Katodritou, E.; Tsitouridis, I.; Hytiroglou, P.; Christakis, J.; Korantzis, I.; Germenis, A. (2007) -
Association of Common Nucleotide-Binding Oligomerization Domain 2 (NOD2) Polymorphisms with the Clinical Phenotype of Antibody Deficiencies
Michopoulos, A.; Papadopoulou-Alataki, A.; Farmaki, E.; Germenis, A. E.; Speletas, M. (2014) -
Association of TLR4-T399I Polymorphism with Chronic Obstructive Pulmonary Disease in Smokers
Speletas, M.; Merentiti, V.; Kostikas, K.; Liadaki, K.; Minas, M.; Gourgoulianis, K.; Germenis, A. E. (2009)Tobacco smoking has been considered the most important risk factor for chronic obstructive pulmonary disease (COPD) development. However, not all smokers develop COPD and other environmental and genetic susceptibility ... -
Clinical immunology quiz - Case 1
Speletas, M.; Kalala, F.; Dalekos, G. (2007) -
Clinical immunology quiz - Case 2: Commentary
Speletas, M.; Kalala, F.; Daniil, Z. (2007) -
Clinical immunology quiz - Case 3
Kalala, F.; Loules, C.; Mamara, A.; Papadakis, E.; Speletas, M. (2007) -
Clinical immunology quiz - Case 4
Kalala, F.; Mamara, A.; Theodoridou, A. T.; Speletas, M. (2008) -
Clinical immunology quiz - Case 5
Loules, G.; Kalala, F.; Mamara, A.; Tsitsami, E.; Speletas, M. (2008) -
Clinical immunology quiz-Case 6
Speletas, M.; Boukas, K.; Louies, G.; Germenis, A. E. (2009) -
A common single nucleotide polymorphism impairs B-cell activating factor receptor's multimerization, contributing to common variable immunodeficiency
Pieper, K.; Rizzi, M.; Speletas, M.; Smulski, C. R.; Sic, H.; Kraus, H.; Salzer, U.; Fiala, G. J.; Schamel, W. W.; Lougaris, V.; Plebani, A.; Hammarstrom, L.; Recher, M.; Germenis, A. E.; Grimbacher, B.; Warnatz, K.; Rolink, A. G.; Schneider, P.; Notarangelo, L. D.; Eibel, H. (2014) -
Deficiency of the B cell-activating factor receptor results in limited CD169+ macrophage function during viral infection
Xu, H. C.; Huang, J.; Khairnar, V.; Duhan, V.; Pandyra, A. A.; Grusdat, M.; Shinde, P.; McIlwain, D. R.; Maney, S. K.; Gommerman, J.; Löhning, M.; Ohashi, P. S.; Mak, T. W.; Pieper, K.; Sic, H.; Speletas, M.; Eibel, H.; Ware, C. F.; Tumanov, A. V.; Kruglov, A. A.; Nedospasov, S. A.; Häusinger, D.; Recher, M.; Lang, K. S.; Lang, P. A. (2015)The B cell-activating factor (BAFF) is critical for B cell development and humoral immunity in mice and humans. While the role of BAFF in B cells has been widely described, its role in innate immunity remains unknown. Using ... -
Endothelin-1 Signaling Promotes Fibrosis In Vitro in a Bronchopulmonary Dysplasia Model by Activating the Extrinsic Coagulation Cascade
Kambas, K.; Chrysanthopoulou, A.; Kourtzelis, I.; Skordala, M.; Mitroulis, I.; Rafail, S.; Vradelis, S.; Sigalas, I.; Wu, Y. Q.; Speletas, M.; Kolios, G.; Ritis, K. (2011)Neonatal respiratory distress syndrome can progress to bronchopulmonary dysplasia (BPD), a serious pulmonary fibrotic disorder. Given the involvement of the extrinsic coagulation cascade in animal models of lung fibrosis, ... -
F12-46C/T polymorphism as modifier of the clinical phenotype of hereditary angioedema
Speletas, M.; Szilágyi, Á; Csuka, D.; Koutsostathis, N.; Psarros, F.; Moldovan, D.; Magerl, M.; Kompoti, M.; Varga, L.; Maurer, M.; Farkas, H.; Germenis, A. E. (2015)The factors influencing the heterogeneous clinical manifestation of hereditary angioedema due to C1-INH deficiency (C1-INH-HAE) represent one of the oldest unsolved problems of the disease. Considering that factor XII ... -
Fast and reliable mutation detection of the complete exon 11-15 JAK2 coding region using non-isotopic RNase cleavage assay (NIRCA)
Kambas, K.; Mitroulis, I.; Kourtzelis, I.; Chrysanthopoulou, A.; Speletas, M.; Ritis, K. (2009)The screening for JAK2 V617F mutation in patients with polycythemia vera, essential thrombocythemia, and idiopathic myelofibrosis offers crucial information for the final diagnosis of these disorders. Recently, several ... -
FIP1L1-PDGFRA molecular analysis in the differential diagnosis of eosinophilia
Loules, G.; Kalala, F.; Giannakoulas, N.; Papadakis, E.; Matsouka, P.; Speletas, M. (2009)Background: Primary eosinophlia associated with the FIP1L1-PDGFRA rearrangement represents a subset of chronic eosinophilic leukaemia (CEL) and affected patients are very sensitive to imatinib treatment. This study was ... -
Foxp3 expression in human cancer cells
Karanikas, V.; Speletas, M.; Zamanakou, M.; Kalala, F.; Loules, G.; Kerenidi, T.; Barda, A. K.; Gourgoulianis, K. I.; Germenis, A. E. (2008)Objective: Transcription factor forkhead box protein 3 (Foxp3) specifically characterizes the thymically derived naturally occurring regulatory T cells (Tregs). Limited evidence indicates that it is also expressed, albeit ... -
Foxp3 Expression in Liver Correlates with the Degree but Not the Cause of Inflammation
Speletas, M.; Argentou, N.; Germanidis, G.; Vasiliadis, T.; Mantzoukis, K.; Patsiaoura, K.; Nikolaidis, P.; Karanikas, V.; Ritis, K.; Germenis, A. E. (2011)Patients with chronic viral hepatitis display increased expression of Foxp3 in liver, suggesting that Tregs expansion contributes to persistent infection. The purpose of this study was to elucidate whether the expression ...