Πλοήγηση ανά Θέμα "RANDOMIZED-TRIAL"
Αποτελέσματα 1-19 από 19
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Accelerated Hypofractionated Whole-Breast Irradiation With Concomitant Daily Boost in Early Breast Cancer
(2015)Objectives:The aim of this study is to evaluate the feasibility and the related toxicity of hypofractionated whole-breast irradiation with a concomitant daily boost in early breast cancer women not eligible for accelerated ... -
Biological importance of reactive oxygen species in relation to difficulties of treating pathologies involving oxidative stress by exogenous antioxidants
(2013)Findings about involvement of reactive oxygen species (ROS) not only in defense processes, but also in a number of pathologies, stimulated discussion about their role in etiopathogenesis of various diseases. Yet questions ... -
Challenges and Choices in Prostate Cancer Irradiation: From the Three Dimensional Conformal Radiotherapy to the Era of Intensity Modulated, Image-Guided and Adaptive Radiation Treatment
(2014)In the last decades the status of radiotherapy was tremendously increased in terms of conformity to the target as well as image-guided techniques in conjunction with intensity-modulated radiotherapy (IMRT). The technological ... -
Comparison of Two Radiotherapeutic Hypofractionated Schedules in the Application of Tumor Bed Boost
(2013)The application of the tumor bed boost by using 2 different hypofractionated planning techniques permit more efficient use of resources in hospitals. The evaluation of the radiation toxicity and the efficacy of the 2 ... -
Docetaxel and Intermittent Erlotinib in Patients with Metastatic Non-small Cell Lung Cancer; A Phase II Study From The Hellenic Cooperative Oncology Group
(2014)Aim: To determine the more effective dosing sequence of intermittent erlotinib and docetaxel for treating chemotherapy-naive patients with advanced Non-Small Cell Lung Cancer (NSCLC). Patients and Methods: Patients were ... -
Endovascular Abdominal Aortic Aneurysm Repair (EVAR) Procedures: Counterbalancing the Benefits With the Costs
(2010)Endovascular abdominal aortic aneurysm (AAA) repair (EVAR) is associated with lower 30-day mortality rates compared with open repair. Despite that, there are no significant differences in mortality rates between the two ... -
Extreme between-study homogeneity in meta-analyses could offer useful insights
(2006)Objectives: Meta-analyses are routinely evaluated for the presence of large between-study heterogeneity. We examined whether it is also important to probe whether there is extreme between-study homogeneity. Study Design: ... -
Improving the Prediction of Spontaneous and Post-thrombolytic Recanalization in Ischemic Stroke Patients
(2015)Background: Endovascular treatment for acute ischemic stroke patients was recently shown to improve recanalization rates and clinical outcome in a well-defined study population. Intravenous thrombolysis (IVT) alone is ... -
Laparoendoscopic rendezvous: an effective alternative to a failed preoperative ERCP in patients with cholecystocholedocholithiasis
(2010)Background Although the ideal management of cholelithiasis and concomitant choledocholithiasis is controversial, the two-stage approach [endoscopic retrograde cholangiopancreatography (ERCP), sphincterotomy, and common ... -
Male Breast Carcinoma: Epidemiology, Risk Factors and Current Therapeutic Approaches
(2012)Male breast cancer is a very rare disease with an incidence of about 0.5-1% comparing with the one of female breast cancer but relatively little is known about its cause. Treatment strategies for breast cancer in males are ... -
Minimally Invasive Surgical Treatments for Benign Prostatic Hyperplasia
(2009)Although transurethral resection of the prostate (TURP) is considered to be the reference standard for minimally invasive surgical treatment (MIST) of lower urinary tract symptoms (LUTS) due to benign prostatic obstruction ... -
Open Versus Tunneling Radial Artery Harvest for Coronary Artery Grafting
(2010)P>We present a less traumatic surgical technique for harvesting the radial artery as a coronary artery bypass graft that does not require any special equipment or skills. We prospectively randomized 40 patients undergoing ... -
Percutaneous Coronary Intervention Versus Optimal Medical Therapy for Prevention of Spontaneous Myocardial Infarction in Subjects With Stable Ischemic Heart Disease
(2013)Background-Contemporary studies have shown that spontaneous but not procedural myocardial infarction (MI) is related to subsequent mortality. Whether percutaneous coronary intervention (PCI) reduces spontaneous (nonprocedural) ... -
Revisiting bleomycin from pathophysiology to safe clinical use
(2013)Bleomycin is a key component of curative chemotherapy regimens employed in the treatment of curable cancers, such as Hodgkin lymphoma (HL) and testicular germ-cell tumours (GCT), yet its use may cause bleomycin-induced ... -
The role of human telomerase catalytic subunit mRNA expression in cervical dysplasias
(2005)Telomerase activity and human telomerase reverse transcriptase (hTERT) mRNA expression were investigated in cervical specimens and were correlated with cytologic findings and the presence of human papilloma virus (HPV) ... -
The Role of Oral Vitamin K Antagonists in the Outcome of Infrainguinal Bypass Procedures
(2014)We investigated the role of oral vitamin K antagonists (VKAs) in graft patency, limb salvage, major and minor bleeding rates in patients undergoing infrainguinal bypass surgery. Five randomized-controlled trials (RCTs; n ... -
The role of second-generation 5-HT3 receptor antagonists in managing chemotherapy-induced nausea and vomiting in hematological malignancies
(2012)Compared with solid tumor patients, those with hematological malignancies are at particular risk of chemotherapy-induced nausea and vomiting (CINV) because of their young age, exposure to highly-emetogenic induction, ... -
Treatment of Low-risk Prostate Cancer with Radical Hypofractionated Accelerated Radiotherapy with Cytoprotection (HypoARC): An Interim Analysis of Toxicity and Efficacy
(2011)Aim: Radiobiological analysis of clinical data suggests that prostate cancer has a low alpha/beta ratio, implying that large radiotherapy fractions may better control the disease. Acceleration of radiotherapy may be also ... -
Venous thromboembolism during air travel: does the existing evidence raise legal implications?
(2009)Venous thromboembolism associated with prolonged sitting during air travel has been reported in the medical literature. The aim of this article was to review whether the existing evidence can raise ethical concerns and ...