Listar por tema "PATHOGENESIS"
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Abdominal aortic aneurysm and abdominal wall hernia as manifestations of a connective tissue disorder
(2011)Background: Abdominal aortic aneurysms (AAAs) and abdominal wall hernias represent chronic degenerative conditions. Both aortic aneurysms and inguinal hernias share common epidemiologic features, and several investigators ... -
Carotid plaque composition in stable and unstable coronary artery disease
(2005)Background Several pieces of evidence suggest that formation of complex atheromatous plaques may be influenced not only by local but also by systemic factors. Methods Twenty-five patients (16 men/9 women, age 63 +/- 10 ... -
Circulating matrix metalloproteinases and their inhibitors in inguinal hernia and abdominal aortic aneurysm
(2011)Aim. There is evidence supporting the role of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) in aortic and abdominal wall connective tissue degeneration, resulting in aneurysm and hernia formation. Furthermore, ... -
Complicated urinary tract infections
(2000)The term complicated urinary tract infection is usually used to convey an infection that occurs in a patient with a structural or functional abnormality impeding urine flow, or in a host with altered defences. The distinction ... -
Crohn's disease-specific anti-CUZD1 pancreatic antibodies are absent in ruminants with paratuberculosis
(2015)Background: Pancreatic autoantibodies (PABs) specifically recognizing GP2 and/or CUZD1 are present in more than 35% of patients with Crohn's disease (CrD). We have recently provided evidence of the presence of GP2-specific ... -
Diagnostic accuracy of biomarkers of oxidative stress in parapneumonic pleural effusions
(2011)P>Background The imbalance between oxidants and antioxidants is referred to as oxidative stress and has been associated with various respiratory disorders. The aim of this study was the assessment of 8-isoprostane (8-iso-PGF(2 ... -
Diagnostic and clinical significance of Crohn's disease-specific anti-MZGP2 pancreatic antibodies by a novel ELISA
(2015)Background: We developed a new IgA and IgG anti-MZGP2 antibody ELISAs based on recombinant isoform-4 of human zymogen granule protein-2 (GP2), which is the major autoantigen of Crohn's disease (CrD)-specific pancreatic ... -
Gilbert Syndrome as a Predisposing Factor for Cholelithiasis Risk in the Greek Adult Population
(2009)We investigated the hypothesis that coinheritance of the common A(TA)(n)TAA promoter mutation at the UGT1A1 locus associated with Gilbert syndrome is a risk factor for gallstone formation in a homogeneous adult population, ... -
Glutathione S-transferase polymorphisms and onset age in alpha-synuclein A53T mutant Parkinson's disease
(2007)Monogenic forms of Parkinson's disease (PD) provide an opportunity to examine mechanisms underlying phenotypic variation. Glutathione S-transferase (GST) has detoxification and antioxidative functions. To screen genetic ... -
High serum levels of HIF-1 alpha in psoriatic patients correlate with an over-expression of IL-6
(2013)Angiogenesis has been considered to be an important step in the initiation and progression of chronic diseases such as psoriasis. The hypoxia inducible factor 1 alpha (HIF-1 alpha), a critical hypoxia-induced factor that ... -
Identification of staphylococci by Phoenix: validation of a new protocol and comparison with Vitek 2
(2010)Because of their frequent isolation in the routine laboratory and their increasing clinical significance, fast and accurate species identification of staphylococci may be required, this can only be achieved by automated ... -
Laryngeal manifestations and pediatric laryngopharyngeal. reflux
(2006)Pediatric laryngopharyngeal reflux (PLPR) refers to the atypical, otorhinolaryngological, and respiratory manifestations of gastroesophageal reflux disease in children. PLPR is believed to be an important inflammatory ... -
Lessons learnt from the autopsies of 445 cases of sudden cardiac death in adults
(2005)Aim To determine the cause of sudden cardiac death in adults who underwent autopsy. Methods Four hundred and forty-five sudden cardiac deaths occurred within 1 h of the symptoms onset, and all other cardiac and noncardiac ... -
Low glucose level and low pH alter the electrochemical function of human parietal pleura
(2007)The aim of the present study was to investigate whether low glucose and pH level, which are usually measured in complicated pleural effusions, alter the electrochemical function of healthy human parietal pleura. Parietal ... -
A matched case-control study of factors associated with retention of fetal membranes in dairy ewes in Southern Greece
(2000)We defined retention of fetal membranes (RFM) in dairy ewes as failure to expel the placenta within 6 h after lambing the last lamb and designed a matched case-control study to identify factors that affect the risk of ... -
Melatonin secretion is impaired in women with preeclampsia and an abnormal circadian blood pressure rhythm
(2014)Non-dipping circadian blood pressure (BP) is a common finding in preeclampsia, accompanied by adverse outcomes. Melatonin plays pivotal role in biological circadian rhythms. This study investigated the relationship between ... -
Microsatellite instability in human atherosclerotic plaques
(1996)The aetiopathology of atherosclerosis remains obscure. Although histologically the accumulation of lipids and the proliferation of the smooth muscle cells represents the main feature of the disease, little is known as ... -
PBC triggers in water reservoirs, coal mining areas and waste disposal sites: From Newcastle to New York
(2010)Various environmental factors have been proposed as triggers of primary biliary cirrhosis (PBC), a progressive autoimmune cholestatic liver disease which is characterised by the destruction of the small intrahepatic bile ... -
Pharmacokinetics and clinical assessment of amoxicillin for the control of necrotic enteritis in broiler-breeders under field conditions
(2015)Necrotic enteritis (NE) is an acute clostridium infection characterised by sudden onset, high mortality and severe necrosis of intestinal mucosa. The present study was conducted to clinically assess the efficacy of amoxicillin ...