Browsing by Author "Mavropoulos, A."
Now showing items 1-13 of 13
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Crohn's disease-specific anti-CUZD1 pancreatic antibodies are absent in ruminants with paratuberculosis
Liaskos, C.; Spyrou, V.; Athanasiou, L. V.; Orfanidou, T.; Mavropoulos, A.; Rigopoulou, E. I.; Amiridis, G. S.; Shoenfeld, Y.; Billinis, C.; Bogdanos, D. P. (2015)Background: Pancreatic autoantibodies (PABs) specifically recognizing GP2 and/or CUZD1 are present in more than 35% of patients with Crohn's disease (CrD). We have recently provided evidence of the presence of GP2-specific ... -
Crohn's disease-specific pancreatic autoantibodies are specifically present in ruminants with paratuberculosis: Implications for the pathogenesis of the human disease
Liaskos, C.; Spyrou, V.; Roggenbuck, D.; Athanasiou, L. V.; Orfanidou, T.; Mavropoulos, A.; Reinhold, D.; Rigopoulou, E. I.; Amiridis, G. S.; Billinis, C.; Bogdanos, D. P. (2013)Mycobacterium avium subspecies paratuberculosis (MAP) induces paratuberculosis (ptb) in ruminants and has clinical and histological features resebling Crohn's disease (CD). Pancreatic autoantibodies (PAB) targeting ... -
Flow Cytometric Detection of p38 MAPK Phosphorylation and Intracellular Cytokine Expression in Peripheral Blood Subpopulations from Patients with Autoimmune Rheumatic Diseases
Mavropoulos, A.; Bogdanos, D. P.; Liaskos, C.; Orfanidou, T.; Simopoulou, T.; Zafiriou, E.; Sakkas, L. I.; Rigopoulou, E. I. (2014)Flow cytometric analysis of p38 mitogen-activated protein kinase (p38 MAPK) signaling cascade is optimally achieved by methanol permeabilization protocols. Such protocols suffer from the difficulties to accurately detect ... -
HELICOBACTER PYLORI AS A TRIGGER OF SYSTEMIC SCLEROSIS: IMMUNOLOGICAL ASPECTS
Liaskos, C.; Varna, A.; Simopoulou, T.; Mavropoulos, A.; Mytilinaiou, M.; Rigopoulou, E. I.; Bogdanos, D. P.; Sakkas, L. I. (2014) -
Human peripheral blood mononuclear cell culture for flow cytometric analysis of phosphorylated mitogen-activated protein kinases
Mavropoulos, A.; Smyk, D.; Rigopoulou, E. I.; Bogdanos, D. P. (2012)Lymphocyte activation and fine tuning of downstream signaling circuits for the regulation of cytokine expression are critical for a successful immune response. Hence, technical protocols permitting simultaneous testing of ... -
Immunopathogenesis of primary biliary cirrhosis: an old wives' tale
Smyk, D. S.; Rigopoulou, E. I.; Lleo, A.; Abeles, R. D.; Mavropoulos, A.; Billinis, C.; Invernizzi, P.; Bogdanos, D. P. (2011)Primary biliary cirrhosis (PBC) is a cholestatic liver disease characterised by the autoimmune destruction of the small intrahepatic bile ducts. The disease has an unpredictable clinical course, but may progress to fibrosis ... -
The immunopathogenetic role of autoantibodies in canine autoimmune hepatitis: Lessons to learn from human autoimmune hepatitis
Liaskos, C.; Mavropoulos, A.; Orfanidou, T.; Spyrou, V.; Athanasiou, L. V.; Billinis, C. (2012)Autoimmune hepatitis (AIH) is not a disease entity restricted to man, but it can be found in other animals including canines. An increasing number of studies have focused on the immunopathogenesis of human autoimmune ... -
MEMORY (CD27+) B CELL IMPAIRMENT IS A CHARACTERISTIC FEATURE OF PATIENTS WITH SYSTEMIC SCLEROSIS AND PULMONARY FIBROSIS
Sakkas, L.; Mavropoulos, A.; Simopoulou, T.; Varna, A.; Liaskos, C.; Katsiari, C.; Bogdanos, D. P. (2014) -
New sensitive technique for the detection of anti-smooth muscle antibodies in autoimmune hepatitis
Liaskos, C.; Mytilinaiou, M. G.; Grammatikopoulos, A.; Smyk, D. S.; Orfanidou, T.; Mavropoulos, A.; Norman, G. L.; Rigopoulou, E. I.; Mieli-Vergani, G.; Bogdanos, D. P.; Vergani, D. (2012) -
P38 MAPK signaling in pemphigus: Implications for skin autoimmunity
Mavropoulos, A.; Orfanidou, T.; Liaskos, C.; Smyk, D. S.; Spyrou, V.; Sakkas, L. I.; Rigopoulou, E. I.; Bogdanos, D. P. (2013)p38 mitogen activated protein kinase (p38 MAPK) signaling plays a major role in the modulation of immune-mediated inflammatory responses and therefore has been linked with several autoimmune diseases. The extent of the ... -
p38 mitogen-activated protein kinase (p38 MAPK)-mediated autoimmunity: Lessons to learn from ANCA vasculitis and pemphigus vulgaris
Mavropoulos, A.; Orfanidou, T.; Liaskos, C.; Smyk, D. S.; Billinis, C.; Blank, M.; Rigopoulou, E. I.; Bogdanos, D. P. (2013)Evidence is beginning to accumulate that p38 mitogen activated protein kinase (p38 MAPK) signaling pathway plays an important role in the regulation of cellular and humoral autoimmune responses. The exact mechanisms and ... -
PHOSHORYLATION OF P38 MAPK IS DETECTABLE IN NKT CELLS OF PATIENTS WITH AUTOIMMUNE HEPATITIS IN WHOM IT MIRRORS DISEASE ACTIVITY
Mavropoulos, A.; Spyrou, E.; Rigopoulou, E. I.; Vergani, D.; Dalekos, G. N.; Bogdanos, D. P. (2010) -
The Role of p38 MAPK in the Aetiopathogenesis of Psoriasis and Psoriatic Arthritis
Mavropoulos, A.; Rigopoulou, E. I.; Liaskos, C.; Bogdanos, D. P.; Sakkas, L. I. (2013)The pathogenetic mechanisms responsible for the induction of immune-mediated disorders, such as psoriasis, remain not well characterized. Molecular signaling pathways are not well described in psoriasis, as well as psoriatic ...