Listar por tema "Immunology"
Mostrando ítems 1-20 de 144
-
ABNORMAL EXPRESSION OF C3ORF9 GENE IN PATIENTS WITH MYELODYSPLASTIC SYNDROMES
(2009)Myelodysplastic Syndrome (MDS) cells present genetic instability and dysregulation of the gene C3ORF9, which was isolated from an MDS cDNA library and codes for a putative protein. We studied the expression of C3ORF9 in ... -
Airway responsiveness: role of inflammation, epithelium damage and smooth muscle tension
(1999)THE purpose of this study was the effect of epithelium damage on mechanical responses of airway smooth muscles under different resting tension. We performed acetylcholine (ACh) (10(-5) M)-induced contraction on tracheal ... -
Angiopoietin-2 associations with the underlying infection and sepsis severity
(2015)Angiopoietin-2 (Ang-2) is an important mediator in sepsis. We have previously shown that endotoxemia levels are related to the underlying infection and affect septic patients' outcome. Based on this background we now ... -
Anti-alpha-actinin antibodies cross-react with Anti-ssDNA antibodies in active autoimmune hepatitis
(2008)Recently, we have observed that the association of anti-F-actin autoantibodies (Abs) with anti-alpha-actinin Abs (double reactivity) was correlated with liver disease activity in autoimmune hepatitis type 1 (AIH-1; Gueguen ... -
Anti-citrullinated peptides as autoantigens in rheumatoid arthritis-relevance to treatment
(2014)Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by the presence of rheumatoid factor (RF) and anti-citrullinated protein/peptide autoantibodies (ACPAs). Citrulline derives from arginine by peptidyl ... -
Asialoglycoprotein receptor (ASGPR) as target autoantigen in liver autoimmunity: Lost and found
(2012)Asialoglycoprotein receptor (ASGPR) has attracted the attention of liver immunologists for many years. This liver-specific lectin was found to be a major B and T cell autoantigenic target in patients with autoimmune liver ... -
Association of biofilm formation and methicillin-resistance with accessory gene regulator (agr) loci in Greek Staphylococcus aureus clones
(2009)Pathogenicity of Staphylococcus aureus is coordinated by the accessory gene regulator (agr) system. Previous studies suggested that agr Group 11 methicillin-resistant S. aureus (MRSA), a polymorphism that has been associated ... -
Association of TLR4-T399I Polymorphism with Chronic Obstructive Pulmonary Disease in Smokers
(2009)Tobacco smoking has been considered the most important risk factor for chronic obstructive pulmonary disease (COPD) development. However, not all smokers develop COPD and other environmental and genetic susceptibility ... -
Attitudes Regarding Occupational Vaccines and Vaccination Coverage Against Vaccine-preventable Diseases Among Healthcare Workers Working in Pediatric Departments in Greece
(2012)We studied the attitudes with regard to occupational vaccines and vaccination coverage among healthcare workers in pediatric departments. Completed vaccination rates were 33%, 33%, 41.7%, 3%, 5.8%, 69.2% and 36.3% against ... -
Autoimmune hepatitis type 1 and primary biliary cirrhosis have distinct bone marrow cytokine production
(2005)We have recently reported differences in the hematopoiesis between autoimmune hepatitis type I (AIH-1) and primary biliary cirrhosis (PBC). In view of the notion that cytokines are regulators of hematopoiesis, we investigated ... -
Autoimmunity and Environment: Am I at risk?
(2012)The complex interplay between environmental factors and genetic susceptibility plays an essential role in disease pathogenesis. This is especially true for autoimmunity, where clinical reports, genomic and epidemiological ... -
Azithromycin reduces the viability of human bronchial smooth muscle cells
(2010)The macrolide antibiotic azithromycin has an antiproliferative and autophagic effect on rabbit tracheal smooth muscle cells (SMCs). The purpose of this study is to investigate the effect of azithromycin on human bronchial ... -
Canine plasmacytic-lymphocytic colitis. A clinicopathologic study of 15 cases
(1998)Clinical, endoscopic and histopathologic findings of 15 cases of canine chronic Plasmacytic-Lymphocytic colitis are presented. The clinical findings were hematochesia, mucus in the stool, tenesmus, diarrhea, vomiting and ... -
CD8+T-cell auto-reactivity is dependent on the expression of the immunoproteasome subunit LMP7 in exposed to lipopolysaccharide antigen presenting cells and epithelial target cells
(2013)Proteasome generates peptides for presentation to CD8+ T-cells by antigen presenting cells (APCs) and peripheral cells. Inflammation alters proteasome to immunoproteasome, producing a different pool of peptides. The effect ... -
Chemokine CXCL-1: activity in the vitreous during proliferative vitreoretinopathy
(2015)The aim of this study was to investigate CXCL-1 chemokine levels in the vitreous during rhegmatogenous retinal detachment (RRD) with and without proliferative vitreoretinopathy (PVR) and identify possible correlations with ... -
Clinical significance of the fluctuation of primary biliary cirrhosis-related autoantibodies during the course of the disease
(2013)Primary biliary cirrhosis (PBC) is a chronic cholestatic disease characterized by the presence of antimitochondrial antibodies (AMA). PBC-specific antinuclear antibodies (ANA) have been characterized and associated with ...