Parcourir par sujet "FACTOR-V-LEIDEN"
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The 2003 Marshall R. Urist Award Paper - Genetic background of osteonecrosis: Associated with thrombophilic mutations?
(2004)Intravascular coagulation is considered a major pathogenetic mechanism for nontraumatic osteonecrosis. The aim of our study was to evaluate the association of thrombophilic factor V G1691A mutation (factor V Leiden) and ... -
Factors associated with the development of superficial vein thrombosis in patients with varicose veins
(2013)Introduction: Superficial vein thrombosis (SVT) is a common and controversial clinical entity. Recent studies have demonstrated that SVT should be seen as a venous thromboembolism (VTE). The objective of this study was to ... -
Genetic risk factors for placental abruption - A HuGE review and meta-analysis
(2008)Background: Although the precise pathophysiology that leads to placental abruption is unknown, there is evidence supporting a genetic etiology. Methods: We searched PubMed and systematically reviewed all case-control studies ... -
Prevalence of thrombophilic mutations in patients with unprovoked thromboembolic disease. A comparative analysis regarding arterial and venous disease
(2012)Background: Thromboembolic disease (TED) represents one of the main reasons of morbitity and mortality in Western World. Venous and arterial thrombotic disorders have long been viewed as separate pathophysiological entities. ... -
Sequence variations in the FII, FV, F13A1, FGB and PAI-1 genes are associated with differences in myocardial perfusion
(2011)Aims: Coronary artery disease (CAD) is a significant cause of morbidity and mortality in modern societies. The association between genetic markers and CAD is still poorly understood. In this study, we evaluated the effect ... -
Superficial Vein Thrombosis in Patients with Varicose Veins: Role of Thrombophilia Factors, Age and Body Mass
(2012)Objectives: To investigate the association of various risk factors including thrombophilia defects, in patients with varicose veins (VVs) and history of episodes of superficial vein thrombosis (SVT). Materials and methods: ... -
Thrombophilia and venous thromboembolism in pregnancy: a meta-analysis of genetic risk
(2015)Three common polymorphic variants, namely Factor V Leiden (FVL), Prothrombin G20210A (PT G20210A) and Methylenetetrahydrofolate Reductase (MTHFR) C677T are candidate genes for venous thromboembolism (VTE) in pregnancy. We ...