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Πλοήγηση ανά Θέμα "remdesivir"

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    • COVID-19 pandemic and cardiovascular disease: where do we stand? 

      Chatzis D.G., Magounaki K.T., Pantazopoulos I.N., Johnson E.O., Tsioufis K.P. (2020)
      Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of coronavirus disease 2019 (COVID-19) which recently has been characterized as a pandemic by the World Health Organization (WHO) having killed ...

    • Drug genetic associations with COVID-19 manifestations: a data mining and network biology approach 

      Charitou T., Kontou P.I., Tamposis I.A., Pavlopoulos G.A., Braliou G.G., Bagos P.G. (2022)
      Available drugs have been used as an urgent attempt through clinical trials to minimize severe cases of hospitalizations with Coronavirus disease (COVID-19), however, there are limited data on common pharmacogenomics ...

    • Incidence and Risk Factors for Blood Stream Infection in Mechanically Ventilated COVID-19 Patients 

      Mantzarlis K., Deskata K., Papaspyrou D., Leontopoulou V., Tsolaki V., Zakynthinos E., Makris D. (2022)
      It is widely known that blood stream infections (BSIs) in critically ill patients may affect mortality, length of stay, or the duration of mechanical ventilation. There is scarce data regarding blood stream infections in ...

    • Interleukin-6 inhibitors reduce mortality in coronavirus disease-2019: An individual patient data meta-analysis from randomized controlled trials 

      Tasoudis P.T., Arvaniti C.K., Adamou A.T., Belios I., Stone J.H., Horick N., Sagris D., Dalekos G.N., Ntaios G. (2022)
      Objective: To assess the efficacy of IL-6 inhibitors compared to standard of care (SOC) in COVID-19 patients. Data Sources: A systematic review of the MEDLINE and Scopus databases (last search: October 8th, 2021) was ...

    • Lessons from pathophysiology: Use of individualized combination treatments with immune interventional agents to tackle severe respiratory failure in patients with COVID-19 

      Dalekos G.N., Stefos A., Georgiadou S., Lygoura V., Michail A., Ntaios G., Samakidou A., Giannoulis G., Gabeta S., Vlychou M., Petinaki E., Leventogiannis K., Giamarellos-Bourboulis E.J., Gatselis N.K. (2021)
      Aims Infection by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) may lead to the development of severe respiratory failure. In hospitalized-patients, prompt interruption of the virus-driven inflammatory process ...

    • Management of covid-19 patients in the emergency department 

      Pantazopoulos I., Tsikrika S., Kolokytha S., Manos E., Porpodis K. (2021)
      COVID-19 is an emerging disease of global public health concern. As the pandemic overwhelmed emergency departments (EDs), a restructuring of emergency care delivery became necessary in many hospitals. Furthermore, with ...

    • Relationship between SARS-CoV-2 infection and the incidence of ventilator-associated lower respiratory tract infections: a European multicenter cohort study 

      Rouzé A., Martin-Loeches I., Povoa P., Makris D., Artigas A., Bouchereau M., Lambiotte F., Metzelard M., Cuchet P., Boulle Geronimi C., Labruyere M., Tamion F., Nyunga M., Luyt C.-E., Labreuche J., Pouly O., Bardin J., Saade A., Asfar P., Baudel J.-L., Beurton A., Garot D., Ioannidou I., Kreitmann L., Llitjos J.-F., Magira E., Mégarbane B., Meguerditchian D., Moglia E., Mekontso-Dessap A., Reignier J., Turpin M., Pierre A., Plantefeve G., Vinsonneau C., Floch P.-E., Weiss N., Ceccato A., Torres A., Duhamel A., Nseir S., Favory R., Preau S., Jourdain M., Poissy J., Bouras C., Saint Leger P., Fodil H., Aptel F., Van Der Linden T., Thille A.W., Azoulay E., Pène F., Razazi K., Bagate F., Contou D., Voiriot G., Thevenin D., Guidet B., Le Guennec L., Kouatchet A., Ehrmann S., Brunin G., Morawiec E., Boyer A., Argaud L., Voicu S., Nieszkowska A., Kowalski B., Goma G., Diaz E., Morales L., Tsolaki V., Gtavriilidis G., Mentzelopoulos S.D., Nora D., Boyd S., Coelho L., Maizel J., Du Cheyron D., Imouloudene M., Quenot J.-P., Guilbert A., Cilloniz C., on behalf of the coVAPid study Group (2021)
      Purpose: Although patients with SARS-CoV-2 infection have several risk factors for ventilator-associated lower respiratory tract infections (VA-LRTI), the reported incidence of hospital-acquired infections is low. We aimed ...

    • Remdesivir-induced Bradycardia is not Associated with Worse Outcome in Patients with COVID-19: A Retrospective Analysis 

      Pantazopoulos I., Mavrovounis G., Dimeas G., Zikos N., Pitsikou M., Rousogianni E., Mermiri M., Michou A., Spanos M., Maniotis C., Chalkias A., Laou E., Zakynthinos G., Chatzis D., Gourgoulianis K. (2022)
      Background: COVID-19, is primarily a respiratory illness but is known to cause extrapulmonary manifestations, especially on the cardiovascular system. Bradycardia is commonly reported in COVID-19 patients despite no prior ...