Πλοήγηση ανά Θέμα "parkinsonism"
Αποτελέσματα 1-14 από 14
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Association between Motor Signs and Cognitive Performance in Cognitively Unimpaired Older Adults: A Cross-Sectional Study Using the NACC Database
(2022)Aiming to examine whether specific motor signs are associated with worse performance in specific cognitive domains among cognitively unimpaired (CU) individuals, we performed a cross-sectional analysis of data from the ... -
Association of the Polygenic Risk Score With the Probability of Prodromal Parkinson’s Disease in Older Adults
(2021)Several studies have investigated the association of the Parkinson’s disease (PD) polygenic risk score (PRS) with several aspects of well-established PD. We sought to evaluate the association of PRS with the prodromal stage ... -
Dietary Inflammatory Index score and prodromal Parkinson's disease incidence: The HELIAD study
(2022)The aim of the present study was to investigate the association of the inflammatory potential of diet with prodromal Parkinson's disease (pPD) probability and incidence among community-dwelling older individuals without ... -
Fahr's syndrome due to hypoparathyroidism revisited: A case of parkinsonism and a review of all published cases
(2021)Introduction: Fahr's syndrome due to hypoparathyroidism refers to bilateral basal ganglia (BG) calcifications and manifests with movement disorders, seizures, cognitive and behavioral symptoms. Case presentation: We report ... -
Human coronaviruses in idiopathic Parkinson's disease: Implications of SARS-CoV-2's modulation of the host's transcriptome
(2021)Objective: A recent study on the effects of SARS-CoV-2 infection on the host's transcriptome indicated the perturbation of several pathways associated with neurodegeneration, including but not limited to Parkinson's and ... -
Late life psychotic features in prodromal Parkinson's disease
(2021)Introduction: Some case series have suggested that psychotic features could occur even before the onset of motor symptoms of Parkinson's Disease (PD). Our aim was to investigate a possible association between psychotic ... -
Motor function and the probability of prodromal Parkinson's disease in older adults
(2019)Background: Identification and characterization of Parkinson's disease (PD) in its prodromal stage is crucial. Objective: The objective of this study was to investigate the association between motor function and the ... -
Neurodegeneration and inflammation—an interesting interplay in parkinson’s disease
(2020)Parkinson’s disease (PD) is a neurodegenerative disorder, caused by, so far, unknown pathogenetic mechanisms. There is no doubt that pro-inflammatory immune-mediated mechanisms are pivotal to the pathogenicity and progression ... -
Plasma Glutathione and Prodromal Parkinson's Disease Probability
(2022)Background: A decrease in glutathione (GSH) levels is considered one of the earliest biochemical changes in Parkinson's disease (PD). Objective: The authors explored the potential role of plasma GSH as a risk/susceptibility ... -
Post-COVID-19 Parkinsonism and Parkinson’s Disease Pathogenesis: The Exosomal Cargo Hypothesis
(2022)Parkinson’s disease (PD) is the second most prevalent neurodegenerative disease after Alzheimer’s disease, globally. Dopaminergic neuron degeneration in substantia nigra pars compacta and aggregation of misfolded alpha-synuclein ... -
SARS-CoV-2 dysregulation of PTBP1 and YWHAE/Z gene expression: A primer of neurodegeneration
(2020)SARS-CoV-2 neurotropism has been increasingly recognized by its imaging and syndromic manifestations in the literature. The purpose of this report is to explore the limited yet salient current evidence that SARS-CoV-2′s ... -
A Swedish family with de novo alpha-synuclein A53T mutation: Evidence for early cortical dysfunction
(2009)A de novo alpha-symaclein A53T (p.Ala53 Th; c.209G > A) mutation has been identified in a Swedish family with autosomal dominant Parkinson's disease (PD). Two affected individuals had early-onset (before 31 and 40 years), ... -
Therapeutic Application of rTMS in Atypical Parkinsonian Disorders
(2021)The terms atypical parkinsonian disorders (APDs) and Parkinson plus syndromes are mainly used to describe the four major entities of sporadic neuronal multisystem degeneration: progressive supranuclear palsy (PSP), ... -
α-Synuclein (SNCA) A30G Mutation as a Cause of a Complex Phenotype Without Parkinsonism
(2021)[No abstract available]