• The effect of a GnRH antagonist on follicle maturation in normal women 

      Pousias S., Messini C.I., Anifandis G., Sveronis G., Georgoulias P., Daponte A., Messinis I.E., Dafopoulos K. (2019)
      Research question: Ganirelix is a gonadotrophin-releasing hormone (GnRH) antagonist used for the prevention of premature LH surge during ovarian stimulation. What is the impact of ganirelix on follicle maturation in normal ...
    • The endocrine effects of multiple folliculogenesis 

      Messinis, I. E. (2011)
      Induction of multiple follicular development is a common practice in IVF programmes. Nevertheless, such an approach is not without implications. Apart from the high multiple pregnancy rate, marked changes in the secretion ...
    • Exogenous progesterone for LH surge prevention is redundant in ovarian stimulation protocols 

      Messinis I.E., Messini C.I., Anifandis G., Daponte A. (2021)
      During ovarian stimulation for IVF–embryo transfer treatment, a premature LH surge may lead to progesterone elevation that disrupts endometrial maturation and affects the probability of pregnancy following fresh embryo ...
    • Purification of a candidate gonadotrophin surge attenuating factor from human follicular fluid 

      Pappa, A.; Seferiadis, K.; Fotsis, T.; Shevchenko, A.; Marselos, M.; Tsolas, O.; E.messinis, I. (1999)
      Gonadotrophin surge attenuating factor (GnSAF) is a new non-steroidal ovarian substance, different from inhibin, which attenuates the pre-ovulatory luteinizing hormone (LH) surge in superovulated women. Human follicular ...