Πλοήγηση ανά Θέμα "graft rejection"
Αποτελέσματα 1-8 από 8
-
“Blame it on the Comorbidities”: A 5-Year Follow-Up of 53 Chronic Dialysis-Dependent Patients Who Underwent Cardiac Surgery
(2016)Objectives This study evaluates midterm survival rates and risk factors for mortality of chronic dialysis-dependent patients undergoing cardiac surgery. Methods Fifty-three dialysis-dependent patients (34 males, aged 67 ± ... -
A comparative analysis between proteasome and immunoproteasome inhibition in cellular and humoral alloimmunity
(2017)Triggered by the successful administration of the proteasome inhibitor bortezomib in kidney transplant recipients with acute or chronic antibody-mediated rejection, we evaluated the effect of the proteasome inhibitor ... -
The effect of anti‑HLA class I antibodies on the immunological properties of human glomerular endothelial cells and their modification by mTOR inhibition or GCN2 kinase activation
(2021)In antibody‑mediated rejection (ABMR), the graft endothelium is at the forefront of the kidney transplant against the assault from the recipient's humoral immune system, and is a target of the latter. The present study ... -
Molecular Aspects of Renal Immunology: Current Status and Future Perspectives
(2022)[No abstract available] -
Patterns of 1,748 Unique Human Alloimmune Responses Seen by Simple Machine Learning Algorithms
(2020)Allele specific antibody response against the polymorphic system of HLA is the allogeneic response marker determining the immunological risk for graft acceptance before and after organ transplantation and therefore routinely ... -
Rituximab Administered for Recurrent Membranous Nephropathy in a Kidney Transplant Recipient Did Not Eliminate Donor-Specific Antibodies
(2022)Chronic active antibody-mediated rejection is the leading cause of kidney transplant failure. Although various immunosuppressive agents have been tested, rituximab included, presently there is no effective treatment. There ... -
A role for human renal tubular epithelial cells in direct allo-recognition by CD4+ T-cells and the effect of ischemia-reperfusion
(2021)Direct allorecognition is the earliest and most potent immune response against a kidney allograft. Currently, it is thought that passenger donor professional antigen-presenting cells (APCs) are responsible. Further, many ... -
A ‘waste product’ to save the day in the field of transplantation: The evolving potential of extracellular vesicles
(2022)Graft rejection and graft-versus-host disease constitute the leading causes of morbidity and early mortality after solid organ and haematopoietic stem cell transplantation, respectively. Despite the current advances in ...