Πλοήγηση ανά Θέμα "glioma"
Αποτελέσματα 1-12 από 12
-
Chimeric stimuli-responsive liposomes as nanocarriers for the delivery of the anti-glioma agent TRAM-34
(2021)Nanocarriers are delivery platforms of drugs, peptides, nucleic acids and other therapeutic molecules that are indicated for severe human diseases. Gliomas are the most frequent type of brain tumor, with glioblastoma being ... -
Efficacy of low dose temozolomide in combination with bortezomib in U87 glioma cells: a flow cytometric analysis
(2015)Introduction: Maximizing responses of malignant gliomas is hampered by resistance to temozolomide (TMZ). Increasing efficacy but not toxicity is a key issue when testing drug combinations. The antimyeloma agent bortezomib ... -
Fluorescent guided surgery in the surgical management of glioma: The dawn of a new era
(2020)[No abstract available] -
Imaging biomarker analysis of advanced multiparametric MRI for glioma grading
(2019)Aims and objectives: To investigate the value of advanced multiparametric MR imaging biomarker analysis based on radiomic features and machine learning classification, in the non-invasive evaluation of tumor heterogeneity ... -
Inferior Longitudinal Fascicle and Reading: Exploring Their Relationship Through a Brain Stimulation Case Study
(2022)Awake brain surgery allows for maximal tumor resection, while minimizing postoperative deficits, even when the tumor is located within eloquent brain regions. In the current study, we present the case of a patient who ... -
Machine learning assisted DSC-MRI radiomics as a tool for glioma classification by grade and mutation status
(2020)Background: Combining MRI techniques with machine learning methodology is rapidly gaining attention as a promising method for staging of brain gliomas. This study assesses the diagnostic value of such a framework applied ... -
Non-genetic risk and protective factors and biomarkers for neurological disorders: a meta-umbrella systematic review of umbrella reviews
(2021)Background: The etiologies of chronic neurological diseases, which heavily contribute to global disease burden, remain far from elucidated. Despite available umbrella reviews on single contributing factors or diseases, no ... -
The role of MiRNA-21 in gliomas: Hope for a novel therapeutic intervention?
(2020)Gliomas are the most common primary brain tumors in adults. They are generally very resistant to treatment and are therefore associated with negative outcomes. MicroRNAs (miRNAs) are small, non-coding RNA molecules that ... -
The role of the t2–flair mismatch sign as an imaging marker of idh status in a mixed population of low-and high-grade gliomas
(2020)Our study evaluated the role of the T2–fluid-attenuated inversion recovery (FLAIR) mismatch sign in detecting isocitrate dehydrogenase (IDH) mutations based on a mixed sample of 24 patients with low-and high-grade gliomas. ... -
The shaping of invasive glioma phenotype by the ubiquitin-proteasome system
(2013)Protein degradation is an indispensable process for cells which is often deregulated in various diseases, including malignant conditions. Depending on the specific cell type and functions of expressed proteins, this ... -
The t2-flair mismatch sign as an imaging indicator of idh-mutant, 1p/19q non-codeleted lower grade gliomas: A systematic review and diagnostic accuracy meta-analysis
(2021)The study’s objective was the evaluation of the diagnostic accuracy of the T2-FLAIR mismatch sign in terms of diagnosing IDH-mutant non-codeleted (IDHmut-Noncodel) lower grade gliomas (LGG) of the brain. We searched the ...