Πλοήγηση ανά Θέμα "cell protection"
Αποτελέσματα 1-6 από 6
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Allopurinol protects human glomerular endothelial cells from high glucose-induced reactive oxygen species generation, p53 overexpression and endothelial dysfunction
(2018)Purpose: Mitochondrial reactive oxygen species (ROS) overproduction in capillary endothelial cells is a prerequisite for the development of diabetic nephropathy. Inhibition of xanthine oxidase, another ROS generator, ... -
The emerging epigenetics of PARK7 and its implication in neurodegenerative disease
(2018)[No abstract available] -
Mortalin-mediated and ERK-controlled targeting of HIF-1α to mitochondria confers resistance to apoptosis under hypoxia
(2017)Hypoxia inducible factor-1 (HIF-1) is the main transcriptional activator of the cellular response to hypoxia and an important target of anticancer therapy. Phosphorylation by ERK1 and/or ERK2 (MAPK3 and MAPK1, respectively; ... -
Seasonal cellular stress responses of commercially important invertebrates at different habitats of the North Aegean Sea
(2020)In many aquatic species, the negative effect of temperature variations has a significant impact on physiological performance since beyond Tp (upper pejus) and Tc (critical temperatures), according to the oxygen- and ... -
The synergistic function of miR-140–5p and miR-146a on TLR4-mediated cytokine secretion in osteoarthritic chondrocytes
(2020)ΜiR-140–5p and miR-146a regulate inflammatory pathways including TLR4/NF-κB signaling and have been found to be involved in OA pathogenesis. In this study, we investigated the effect of the synergistic function of miR-140–5p ... -
Vegetable organosulfur compounds and their health promoting effects
(2017)Background: Trends in modern pharmaceutical science show an increase in demand for new drugs and diet supplements derived from natural products, while during the last decades, great research is conducted regarding the ...