Πλοήγηση ανά Θέμα "biochemical analysis"

Affinity crystallography reveals the bioactive compounds of industrial juicing byproducts of Punica granatum for glycogen phosphorylase

Stravodimos G.A., Kantsadi A.L., Apostolou A., Kyriakis E., Kafaski-Kanelli V.-N., Solovou T., Gatzona P., Liggri P.G.V., Theofanous S., Gorgogietas V.A., Kissa A., Psachoula C., Lemonakis A., Chatzileontiadou D.S.M., Psarra A.-M.G., Skamnaki V.T., Haroutounian S.A., Leonidas D.E. (2018)

Background: Glycogen phosphorylase (GP) is a pharmaceutical target for the discovery of new antihyperglycaemic agents. Punica granatum is a well-known plant for its potent antioxidant and antimicrobial activities but so ...

Altered DNA methylation pattern characterizes the peripheral immune cells of patients with autoimmune hepatitis

Zachou K., Arvaniti P., Lyberopoulou A., Sevdali E., Speletas M., Ioannou M., Koukoulis G.K., Renaudineau Y., Dalekos G.N. (2022)

Background and Aims: Little is known about the impact of DNA methylation modifications on autoimmune hepatitis (AIH) pathogenesis and therapeutic response. We investigated the potential alterations of DNA methylation in ...

Biochemical and in silico identification of the active site and the catalytic mechanism of the circadian deadenylase HESPERIN

Beta R.A.A., Kyritsis A., Douka V., Papanastasi E., Rizouli M., Leonidas D.D., Vlachakis D., Balatsos N.A.A. (2022)

The 24-h molecular clock is based on the stability of rhythmically expressed transcripts. The shortening of the poly(A) tail of mRNAs is often the first and rate-limiting step that determines the lifespan of a mRNA and is ...

Blood cell count and morphology, and vitamin B12 concentration in pre- and post-weaned calves

Katsogiannou E.G., Katsoulos P.D., Ziogas C., Naskou M.C., Christodoulopoulos G., Polizopoulou Z.S., Tzivara A., Athanasiou L.V. (2021)

Haematological indicators may resent physiological variation by age. Vitamin B12 promotes haematopoiesis. The aims of this study were: 1) to compare the values of the haematological variables and the concentration of vitamin ...

Chemical Characterisation-Biological Evaluation of Greek Cultivar Cardoon Seeds (Cynara cardunculus)A By-product with Potential High Added Value

Graikou K., Kourti P.-M., Zengin G., Gortzi O., Danalatos N., Chinou I. (2021)

Cynara cardunculus (artichoke) is a perennial plant of the Mediterranean basin, known since antiquity as food and for its therapeutic properties. Cynara is a relatively small genus with two cultivated species and one wild ...

Comparison of the Efficacy of Intramammary or Injectable Antibiotic Administration against Staphylococcal Mastitis in Ewes

Vasileiou N.G.C., Fthenakis G.C., Mavrogianni V.S. (2022)

The objectives of the work were (a) to compare the efficacy of two routes for antibiotic administration in the treatment of mastitis in ewes and (b) to assess the potential importance of the timing of the initiation of the ...

Complete surgical excision versus Penrose drainage for the treatment of elbow hygroma in 19 dogs (1997 to 2014)

Angelou V., Papazoglou L.G., Tsioli V., Psalla D., Anagnostou T., Chatzimisios K., Pavlidis L. (2020)

Objectives: To report results of surgical excision and Penrose drainage for the treatment of elbow hygromas in dogs. Materials and Methods: Retrospective review of the clinical records of 19 dogs with elbow hygromas treated ...

COVID-19 Smart Diagnosis in the Emergency Department: all-in in Practice

Mouliou D.S., Pantazopoulos I., Gourgoulianis K.I. (2022)

Introduction: Coronavirus Disease 19 (COVID-19) diagnosis has been a major problem in most Emergency Departments (EDs) and other senior care facilities. Various clinical manifestations, and the several radiologic and ...

Effects of Age and Sex of Response to Ursodeoxycholic Acid and Transplant-free Survival in Patients With Primary Biliary Cholangitis

Cheung A.C., Lammers W.J., Murillo Perez C.F., van Buuren H.R., Gulamhusein A., Trivedi P.J., Lazaridis K.N., Ponsioen C.Y., Floreani A., Hirschfield G.M., Corpechot C., Mayo M.J., Invernizzi P., Battezzati P.M., Parés A., Nevens F., Thorburn D., Mason A.L., Carbone M., Kowdley K.V., Bruns T., Dalekos G.N., Gatselis N.K., Verhelst X., Lindor K.D., Lleo A., Poupon R., Janssen H.L.A., Hansen B.E., Global PBC Study Group (2019)

Background & Aims: Primary biliary cholangitis (PBC) predominantly affects middle-aged women; there are few data on disease phenotypes and outcomes of PBC in men and younger patients. We investigated whether differences ...

Fasting-mediated metabolic and toxicity reprogramming impacts circulating microRNA levels in humans

Ravanidis S., Grundler F., de Toledo F.W., Dimitriou E., Tekos F., Skaperda Z., Kouretas D., Doxakis E. (2021)

It is well-established that long-term fasting improves metabolic health, enhances the total antioxidant capacity and increases well-being. MicroRNAs oversee energy homeostasis and metabolic processes and are widely used ...

Fertility rate of short-term progestagen pretreated ewes in relation to breed: A field study

Papadopoulos S., Deligiannis C., Theodosiadou E.K., Kantas D., Th. L., Goulas P., Fthenakis G.C., Valasi I. (2017)

The effect of short-term instead of long-term progestagen treatment on fertility of Karagouniko and Chios ewes, after natural mating or artificial insemination, was investigated. Two experiments were performed during the ...

First report of uncinaria hamiltoni in orphan eastern mediterranean monk seal pups in greece and its clinical significance

Komnenou A.Th., Gkafas G.A., Kofidou E., Sarantopoulou J., Exadactylos A., Tounta E., Koemtzopoulos K., Dendrinos P., Karamanlidis A.A., Gulland F., Papadopoulos E. (2021)

The Mediterranean monk seal (Monachus monachus) is classified by the IUCN as “endangered,” with a global population estimated to number fewer than 800 individuals. Our understanding of the biology and health status of the ...

The laboratory diagnostic approach to thoracic and abdominal effusions in the dog, cat, and horse

Athanasiou L.V., Spyropoulou M., Meichner K. (2019)

Cases involving pleural and peritoneal effusions occur relatively frequently in clinical practice. Determining the underlying etiology in these cases relies mainly on fluid analysis. The technique used for obtaining the ...

Lettuce facing microcystins-rich irrigation water at different developmental stages: Effects on plant performance and microcystins bioaccumulation

Levizou E., Statiris G., Papadimitriou T., Laspidou C.S., Kormas K.A. (2017)

This study investigated the microcystins (MCs)-rich irrigation water effect on lettuce of different developmental stages, i.e. during a two months period, covering the whole period from seed germination to harvest at ...

Optimization of Recombinant Membrane Protein Production in the Engineered Escherichia coli Strains SuptoxD and SuptoxR

Michou M., Kapsalis C., Pliotas C., Skretas G. (2019)

Membrane proteins (MPs) execute a wide variety of critical biological functions in all living organisms and constitute approximately half of current targets for drug discovery. As in the case of soluble proteins, the ...

A prospective epidemiological, clinical, and clinicopathologic study of feline leukemia virus and feline immunodeficiency virus infection in 435 cats from Greece

Kokkinaki K.G., Saridomichelakis M.N., Leontides L., Mylonakis M.E., Konstantinidis A.O., Steiner J.M., Suchodolski J.S., Xenoulis P.G. (2021)

Feline leukemia virus (FeLV) and feline immunodeficiency virus (FIV) are retroviruses causing significant morbidity and mortality in cats. The aim of this study was to describe the epidemiological, clinical and clinicopathologic ...

Proteomic analysis of the mitochondrial glucocorticoid receptor interacting proteins reveals pyruvate dehydrogenase and mitochondrial 60 kDa heat shock protein as potent binding partners

Karra A.G., Sioutopoulou A., Gorgogietas V., Samiotaki M., Panayotou G., Psarra A.-M.G. (2022)

Glucocorticoids are steroid hormones that regulate plethora biological actions such as growth and metabolism, immune response, and apoptosis. Glucocorticoids actions are mediated via glucocorticoid receptors which act ...