Sfoglia per Soggetto "antibody"

Alpha-actinin: A multidisciplinary protein with important role in B-cell driven autoimmunity

Kikonomou, K. G.; Zachou, K.; Dalekos, G. N. (2011)

Alpha-actinin (α-actinin) is a ubiquitous cytoskeletal protein, which belongs to the superfamily of filamentous actin (F-actin) crosslinking proteins. It is present in multiple subcellular regions of both muscle and ...

Autoimmune hepatitis-specific antibodies against soluble liver antigen and liver cytosol type 1 in patients with chronic viral hepatitis

Rigopoulou, E. I.; Mytilinaiou, M.; Romanidou, O.; Liaskos, C.; Dalekos, G. N. (2007)

Background. Non-organ specific autoantibodies are highly prevalent in patients with chronic hepatitis C (HCV). Among them, anti-liver kidney microsomal type 1 (LKM1) antibody - the serological marker of type 2 autoimmune ...

Cross-Sectional Serosurvey and Risk Factors Associated with the Presence of Toxoplasma gondii Antibodies in Pigs in Greece

Papatsiros V.G., Athanasiou L.V., Stougiou D., Papadopoulos E., Maragkakis G.G., Katsoulos P.D., Lefkaditis M., Kantas D., Tzika E.D., Tassis P.D., Boutsini S. (2016)

Introduction: Toxoplasmosis is a worldwide reported zoonotic infection caused by the protozoon Toxoplasma gondii. Pigs may become infected by ingesting feed or water contaminated with cat faeces, by cannibalism, and/or by ...

Cytochrome P450 2A6: a new hepatic autoantigen in patients with chronic hepatitis C virus infection

Dalekos, G. N.; Obermayer-Straub, P.; Bartels, M.; Maeda, T.; Kayser, A.; Braun, S.; Loges, S.; Schmidt, E.; Gershwin, M. E.; Manns, M. P. (2003)

Background/Aims: Cytochromes P4502A6 (CYP2A6) and P4501A2 (CYP1A2) were described as hepatic autoantigens in the autoimmune polyglandular syndrome type-1 (APS-1). We evaluated the significance of anti-CYP2A6 and anti-CYP1A2 ...

Defining antibody seroprevalence and duration of humoral responses to sars-cov-2 infection and/or vaccination in a greek community

Kotsiou O.S., Papagiannis D., Fradelos E.C., Siachpazidou D.I., Perlepe G., Miziou A., Kyritsis A., Vavougios G.D., Kalantzis G., Gourgoulianis K.I. (2022)

Background: In this work we aimed to evaluate antibody-response longevity to SARS-CoV-2 infection and/or vaccination in one of the Greek communities that was worst hit by the pandemic, Deskati, five months after a previous ...

Detection of Antibodies Against Toxoplasma gondii in Filter Paper-Dried Blood Dot Spots Compared with Serum in Pigs and Assessment of Variation Associated with Packed Cell Volume

Athanasiou L.V., Katsogiannou E.G., Tsokana C.N., Dedousi A., Boutsini S., Papakonstantinou G., Papatsiros V.G. (2022)

The aim of this study was to assess the agreement between anti-Toxoplasma gondii IgG antibody detection in serum and filter paper (FP) blood spots using the indirect immunofluorescence antibody assay (IFA) and to evaluate ...

Diagnostic and clinical significance of Crohn's disease-specific pancreatic anti-GP2 and anti-CUZD1 antibodies

Pavlidis P., Komorowski L., Teegen B., Liaskos C., Koutsoumpas A.L., Smyk D.S., Perricone C., Mytilinaiou M.G., Stocker W., Forbes A., Bogdanos D.P. (2016)

Background: Pancreatic autoantibodies (PAB) targeting GP2 and CUZD1 are Crohn's disease (CrD)-markers. The clinical significance of anti-GP2 antibodies has been assessed, but that of anti-CUZD1 remains elusive. The aim of ...

Effects of Exercise and Physical Activity Levels on Vaccination Efficacy: A Systematic Review and Meta-Analysis

Dinas P.C., Koutedakis Y., Ioannou L.G., Metsios G., Kitas G.D. (2022)

Objective: We examined whether different intensities of exercise and/or physical activity (PA) levels affected and/or associated with vaccination efficacy. Methods: A systematic review and meta-analysis was conducted and ...

Efficacy of an AS03 A-adjuvanted split H5N1 influenza vaccine against an antigenically distinct low pathogenic H5N1 virus in pigs

De Vleeschauwer, A. R.; Baras, B.; Kyriakis, C. S.; Jacob, V.; Planty, C.; Giannini, S. L.; Mossman, S.; Van Reeth, K. (2012)

We used the pig model of influenza to examine the efficacy of an AS03 A-adjuvanted split H5N1 (A/Indonesia/05/2005) vaccine against challenge with a low pathogenic (LP) H5N1 avian influenza (AI) virus (duck/Minnesota/1525/1981) ...

Epidemiological investigation of Legionella pneumophila serogroup 2 to 14 isolates from water samples by amplified fragment length polymorphism and sequence-based typing and detection of virulence traits

Katsiaflaka A., Pournaras S., Kristo I., Mouchtouri V.A., Kyritsi M., Velonakis E., Vatopoulos A.C., Hadjichristodoulou C. (2016)

The aim of this study is to explore the dispersion, clonality, and virulence of Legionella pneumophila serogroups 2 to 14 in the Greek environment. Eighty L. pneumophila serogroup 2 to 14 strains isolated from water ...

Interstitial lung disease in anti-synthetase syndrome

Kourkouni E., Mitsogiannis G., Simopoulou T., Liaskos C., Katsiari C.G., Daniil Z., Gourgoulianis K., Bogdanos D.P., Sakkas L.I. (2019)

Anti-synthetase syndrome is an autoimmune disorder characterized by the presence of autoantibodies against aminoacyl transfer RNA (tRNA) synthetases, and myositis, interstitial lung disease (ILD), arthritis, fever and ...

Lessons We Have Learned Regarding Seroprevalence in High and Low SARS-CoV-2 Contexts in Greece before the Omicron Pandemic Wave

Kotsiou O.S., Vavougios G.D., Papagiannis D., Matsiatsiou E., Avgeri D., Fradelos E.C., Siachpazidou D.I., Perlepe G., Miziou A., Kyritsis A., Gogou E., Kalampokas S., Kalantzis G., Kotsios V.S., Gourgoulianis K.I. (2022)

Background: Antibody seroprevalence in rural communities remains poorly investigated. We compared the SARS-CoV-2 seroprevalence in two Greek communities in June and July 2021 after the end of the Delta-driven pandemic wave ...

Low seropositivity for SARS-CoV-2 antibodies among healthcare workers after the first COVID-19 pandemic wave in Greece

Galanis P., Kaitelidou D., Prezerakos P., Kotsiopoulos I., Siskou O., Konstantakopoulou O., Hadjichristodoulou C., Tsiodras S. (2021)

Objectives: To estimate the prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seropositivity among healthcare workers (HCWs) in Greece and to identify high-risk groups in healthcare facilities. ...

Major vault protein/lung resistance related protein: A novel biomarker for rheumatoid arthritis

Marinou D., Katsifis G., Barouta G., Liaskos C., Sakkas L.I., Tsakris A., Routsias J.G. (2021)

Objective Rheumatoid arthritis (RA) can lead to joint destruction and early institution of effective treatment can preserve joint function. Biomarkers can establish early diagnosis and predict effect of treatment. Vault ...

Occult hepatitis B virus infection in Greek patients with chronic hepatitis C and in patients with diverse nonviral hepatic diseases

Georgiadou, S. P.; Zachou, K.; Rigopoulou, E.; Liaskos, C.; Mina, P.; Gerovasilis, F.; Makri, E.; Dalekos, G. N. (2004)

Occult hepatitis B virus (HBV) infection has been reported in patients with chronic hepatitis C who are negative for HBV surface antigen (HBsAg). However, the significance of 'silent' HBV in hepatitis C virus (HCV) infection ...

Pancreatic anti-GP2 and anti-Saccharomyces cerevisiae antibodies in ruminants with paratuberculosis: A better understanding of the immunopathogenesis of Crohn's disease

Liaskos C., Gkoutzourelas A., Spyrou V., Koutsoumpas A., Athanasiou L.V., Amiridis G.S., Billinis C., Bogdanos D.P. (2020)

Introduction: Ruminants (cattle and sheep) with Mycobacterium avium (MAP)-induced paratuberculosis (ptb), the ruminant model of Crohn's disease (CD), exhibit pancreatic specific autoantibodies (PAB) against GP2 but not ...

Radiolabeled mAbs as Molecular Imaging and/or Therapy Agents Targeting PSMA

Psimadas D., Valotassiou V., Alexiou S., Tsougos I., Georgoulias P. (2018)

Molecular imaging and therapy is a rapidly evolving field in research and clinical medicine. The use of the exciting and attractive properties of radioisotopes for imaging and therapy has made Nuclear Medicine very significant ...

Rituximab Administered for Recurrent Membranous Nephropathy in a Kidney Transplant Recipient Did Not Eliminate Donor-Specific Antibodies

Giannopoulou M., Tarassi K., Tsouka G., Christodoulidou C., Stefanidis I., Eleftheriadis T. (2022)

Chronic active antibody-mediated rejection is the leading cause of kidney transplant failure. Although various immunosuppressive agents have been tested, rituximab included, presently there is no effective treatment. There ...

Serological Evidence of Pandemic H1N1 Influenza Virus Infections in Greek Swine

Kyriakis C.S., Papatsiros V.G., Athanasiou L.V., Valiakos G., Brown I.H., Simon G., Van Reeth K., Tsiodras S., Spyrou V., Billinis C. (2016)

The introduction of the 2009 pandemic H1N1 (pH1N1) influenza virus in pigs changed the epidemiology of influenza A viruses (IAVs) in swine in Europe and the rest of the world. Previously, three IAV subtypes were found in ...

A study of antigen-specific anti-cytomegalovirus antibody reactivity in patients with systemic sclerosis and concomitant anti-Ro52 antibodies

Gkoutzourelas A., Liaskos C., Simopoulou T., Katsiari C., Efthymiou G., Scheper T., Meyer W., Tsirogianni A., Tsigalou C., Dardiotis E., Daoussis D., Sakkas L.I., Bogdanos D.P. (2020)

Anti-Ro52 autoantibody (autoAb), highly prevalent in Sjogren’s syndrome (SjS) and systemic lupus erythematosus (SLE), is also frequent in systemic sclerosis (SSc). Viral agents, such as human cytomegalovirus (HCMV), have ...