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Halogen-substituted (C-beta-D-glucopyranosyl)-hydroquinone regioisomers: Synthesis, enzymatic evaluation and their binding to glycogen phosphorylase

Alexacou, K. M.; Zhang, Y. Z.; Praly, J. P.; Zographos, S. E.; Chrysina, E. D.; Oikonomakos, N. G.; Leonidas, D. D. (2011)

Electrophilic halogenation of C-(2,3,4,6-tetra-O-acetyl-b-D-glucopyranosyl) 1,4-dimethoxybenzene (1) afforded regioselectively products halogenated at the para position to the D-glucosyl moiety (8, 9) that were deacetylated ...