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Listar por tema "Ischemic Stroke"

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    • Adherence to oral anticoagulation in ischemic stroke patients with atrial fibrillation 

      Tiili P., Leventis I., Kinnunen J., Svedjebäck I., Lehto M., Karagkiozi E., Sagris D., Ntaios G., Putaala J. (2021)
      Background: Non-vitamin K antagonist oral anticoagulants (NOAC) have superior safety and comparable efficacy profile compared to vitamin-K antagonists (VKAs), with more convenient dosing schemes. However, issues with ...

    • Assessment of the reporting quality of double-blind RCTs for ischemic stroke based on the CONSORT statement 

      Kodounis M., Liampas I.N., Constantinidis T.S., Siokas V., Mentis A.-F.A., Aloizou A.-M., Xiromerisiou G., Zintzaras E., Hadjigeorgiou G.M., Dardiotis E. (2020)
      Background-Purpose: It is critical that Randomized Controlled Trials(RCTs) present complete and transparent reporting. The present study aims to determine the reporting quality of double-blind RCTs for medicinal interventions ...

    • Comparison of Risk of Serious Cardiovascular Events after Hemorrhagic versus Ischemic Stroke: A Population-Based Study 

      Akyea R.K., Georgiopoulos G., Iyen B., Kai J., Qureshi N., Ntaios G. (2022)
      Background  Patients with ischemic stroke are considered a very high risk population for subsequent cardiovascular events and guidelines recommend intensive preventive strategies. However, there is no clear recommendation ...

    • COVID-19 and ischemic stroke 

      Sagris D., Papanikolaou A., Kvernland A., Korompoki E., Frontera J.A., Troxel A.B., Gavriatopoulou M., Milionis H., Lip G.Y.H., Michel P., Yaghi S., Ntaios G. (2021)
      Since the onset of the COVID-19 pandemic, a substantial proportion of COVID-19 patients had documented thrombotic complications and ischemic stroke. Several mechanisms related to immune-mediated thrombosis, the renin ...

    • Effectiveness and safety of intracranial events associated with the use of direct oral anticoagulants for atrial fibrillation: A systematic review and meta-analysis of 92 studies 

      Archontakis-Barakakis P., Li W., Kalaitzoglou D., Tzelves L., Manolopoulos A., Giannopoulos S., Giamouzis G., Giannakoulas G., Batsidis A., Palaiodimos L., Ntaios G., Lip G.Y.H., Kokkinidis D.G. (2022)
      Aims: Observational studies have investigated the effectiveness and safety of direct oral anticoagulants (DOACs) and vitamin K antagonists (VKAs) used in nonvalvular atrial fibrillation. We performed a systematic review ...

    • EndoVAscular treatment and ThRombolysis for Ischemic Stroke Patients (EVA-TRISP) registry: Basis and methodology of a pan-European prospective ischaemic stroke revascularisation treatment registry 

      Nordanstig A., Curtze S., Gensicke H., Zinkstok S.M., Erdur H., Karlsson C., Karlsson J.-E., Martinez-Majander N., Sibolt G., Lyrer P., Traenka C., Baharoglu M.I., Scheitz J.F., Bricout N., Hénon H., Leys D., Eskandari A., Michel P., Hametner C., Ringleb P.A., Arnold M., Fischer U., Sarikaya H., Seiffge D.J., Pezzini A., Zini A., Padjen V., Jovanovic D.R., Luft A., Wegener S., Kellert L., Feil K., Kägi G., Rentzos A., Lappalainen K., Leker R.R., Cohen J.E., Gomori J., Brehm A., Liman J., Psychogios M., Kastrup A., Papanagiotou P., Gralla J., Magoni M., Majoie C.B.L.M., Bohner G., Vukasinovic I., Cvetic V., Weber J., Kulcsar Z., Bendszus M., Möhlenbruch M., Ntaios G., Kapsalaki E., Jood K., Nolte C.H., Nederkoorn P.J.J., Engelter S., Strbian D., Tatlisumak T. (2021)
      Purpose The Thrombolysis in Ischemic Stroke Patients (TRISP) collaboration was a concerted effort initiated in 2010 with the purpose to address relevant research questions about the effectiveness and safety of intravenous ...

    • Intravenous Thrombolysis in Patients With Ischemic Stroke Aged ≥90 Years: A Cohort Study From the TRISP Collaboration 

      Altersberger V.L., Rusche N., Martinez-Majander N., Hametner C., Scheitz J.F., Henon H., Dell'acqua M.L., Strambo D., Stolp J., Heldner M.R., Grisendi I., Jovanovic D.R., Bejot Y., Pezzini A., Leker R.R., Kägi G., Wegener S., Cereda C.W., Lindgren E., Ntaios G., Piot I., Polymeris A.A., Lyrer P.A., Räty S., Sibolt G., Tiainen M., Heyse M., Erdur H., Kaaouana O., Padjen V., Zedde M., Arnold M., Nederkoorn P.J., Michel P., Bigliardi G., Zini A., Cordonnier C., Nolte C.H., Ringleb P.A., Curtze S., Engelter S.T., Gensicke H., for the Thrombolysis in Stroke Patients (TRISP) Collaborators (2022)
      Background: The probability to receive intravenous thrombolysis (IVT) for treatment of acute ischemic stroke declines with increasing age and is consequently the lowest in very elderly patients. Safety concerns likely ...

    • It is safe to use transdermal glyceryl trinitrate to lower blood pressure in patients with acute ischaemic stroke with carotid stenosis 

      Appleton J.P., Woodhouse L.J., Belcher A., Bereczki D., Berge E., Caso V., Chang H.M., Christensen H.K., Collins R., Gommans J., Laska A.C., Ntaios G., Ozturk S., Sare G.M., Szatmari S., Wang Y., Wardlaw J.M., Sprigg N., Bath P.M. (2019)
      Background There is concern that blood pressure (BP) lowering in acute stroke may compromise cerebral perfusion and worsen outcome in the presence of carotid stenosis. We assessed the effect of glyceryl trinitrate (GTN) ...

    • Machine-Learning-Derived Model for the Stratification of Cardiovascular risk in Patients with Ischemic Stroke 

      Ntaios G., Sagris D., Kallipolitis A., Karagkiozi E., Korompoki E., Manios E., Plagianakos V., Vemmos K., Maglogiannis I. (2021)
      Background Stratification of cardiovascular risk in patients with ischemic stroke is important as it may inform management strategies. We aimed to develop a machine-learning-derived prognostic model for the prediction of ...

    • Measurement of Midregional Pro-Atrial Natriuretic Peptide to Discover Atrial Fibrillation in Patients With Ischemic Stroke 

      Schweizer J., Arnold M., König I.R., Bicvic A., Westphal L.P., Schütz V., Inauen C., Scherrer N., Luft A., Galovic M., Ferreira Atuesta C., Pokorny T., Arnold M., Fischer U., Bonati L.H., De Marchis G.M., Kahles T., Nedeltchev K., Cereda C.W., Kägi G., Bustamante A., Montaner J., Ntaios G., Sagris D., Foerch C., Spanaus K., von Eckardstein A., Katan M. (2022)
      Background: Midregional pro-atrial natriuretic peptide (MR-proANP) is a promising biomarker to differentiate the underlying etiology of acute ischemic stroke (AIS). Objectives: This study aimed to determine the role of ...

    • Prolonged Cardiac Monitoring and Stroke Recurrence: A Meta-analysis 

      Tsivgoulis G., Triantafyllou S., Palaiodimou L., Grory B.M., Deftereos S., Köhrmann M., Dilaveris P., Ricci B., Tsioufis K., Cutting S., Magiorkinis G., Krogias C., Schellinger P.D., Dardiotis E., Rodriguez-Campello A., Cuadrado-Godia E., Aguiar De Sousa D., Sharma M., Gladstone D.J., Sanna T., Wachter R., Furie K.L., Alexandrov A.V., Yaghi S., Katsanos A.H. (2022)
      Background and ObjectivesProlonged poststroke cardiac rhythm monitoring (PCM) reveals a substantial proportion of patients with ischemic stroke (IS) with atrial fibrillation (AF) not detected by conventional rhythm monitoring ...

    • Rationale and design of the AXIOMATIC-SSP phase II trial: Antithrombotic treatment with factor XIa inhibition to Optimize Management of Acute Thromboembolic events for Secondary Stroke Prevention 

      Sharma M., Molina C.A., Toyoda K., Bereczki D., Kasner S.E., Lutsep H.L., Tsivgoulis G., Ntaios G., Czlonkowska A., Shuaib A., Amarenco P., Endres M., Diener H.C., Gailani D., Kahl A., Donovan M., Perera V., Li D., Hankey G.J. (2022)
      Background: Individuals with ischemic stroke or transient ischemic attack (TIA) have a high early risk of ischemic stroke despite dual antiplatelet therapy. The risk of ischemic stroke, and associated disability, represents ...

    • Recommendations for lipid modification in patients with ischemic stroke or transient ischemic attack: A clinical guide by the Hellenic Stroke Organization and the Hellenic Atherosclerosis Society 

      Sagris D., Ntaios G., Georgiopoulos G., Kakaletsis N., Elisaf M., Katsiki N., Korompoki E., Kypreos K.E., Boutari C., Bilianou H., Makaritsis K., Nomikos T., Papavasileiou V., Pitsavos C., Plomaritoglou A., Spengos K., Tziomalos K., Tselepis A., Vemmos K., Liberopoulos E., Milionis H. (2021)
      This document presents the consensus recommendations of the Hellenic Stroke Organization and the Hellenic Atherosclerosis Society for lipid modification in patients with ischemic stroke or transient ischemic attack. This ...

    • Recurrent Ischemic Stroke and Bleeding in Patients With Atrial Fibrillation Who Suffered an Acute Stroke While on Treatment With Nonvitamin K Antagonist Oral Anticoagulants: The RENO-EXTEND Study 

      Paciaroni M., Caso V., Agnelli G., Mosconi M.G., Giustozzi M., Seiffge D.J., Engelter S.T., Lyrer P., Polymeris A.A., Kriemler L., Zietz A., Putaala J., Strbian D., Tomppo L., Michel P., Strambo D., Salerno A., Remillard S., Buehrer M., Bavaud O., Vanacker P., Zuurbier S., Yperzeele L., Loos C.M.J., Cappellari M., Emiliani A., Zedde M., Abdul-Rahim A., Dawson J., Cronshaw R., Schirinzi E., Del Sette M., Stretz C., Kala N., Reznik M., Schomer A., Grory B.M., Jayaraman M., Mctaggart R., Yaghi S., Furie K.L., Masotti L., Grifoni E., Toni D., Risitano A., Falcou A., Petraglia L., Lotti E.M., Padroni M., Pavolucci L., Lochner P., Silvestrelli G., Ciccone A., Alberti A., Venti M., Traballi L., Urbini C., Kargiotis O., Rocco A., Diomedi M., Marcheselli S., Caliandro P., Zauli A., Reale G., Antonenko K., Rota E., Tassinari T., Saia V., Palmerini F., Aridon P., Arnao V., Monaco S., Cottone S., Baldi A., D'Amore C., Ageno W., Pegoraro S., Ntaios G., Sagris D., Giannopoulos S., Kosmidou M., Ntais E., Romoli M., Pantoni L., Rosa S., Bertora P., Chiti A., Canavero I., Saggese C.E., Plocco M., Giorli E., Palaiodimou L., Bakola E., Tsivgoulis G., Bandini F., Gasparro A., Terruso V., Mannino M., Pezzini A., Ornello R., Sacco S., Popovic N., Scoditti U., Genovese A., Denti L., Flomin Y., Mancuso M., Ferrari E., Caselli M.C., Ulivi L., Giannini N., De Marchis G.M. (2022)
      BACKGROUND: In patients with atrial fibrillation who suffered an ischemic stroke while on treatment with nonvitamin K antagonist oral anticoagulants, rates and determinants of recurrent ischemic events and major bleedings ...

    • Review and update of the concept of embolic stroke of undetermined source 

      Diener H.-C., Easton J.D., Hart R.G., Kasner S., Kamel H., Ntaios G. (2022)
      Ischaemic strokes have traditionally been classified according to the TOAST criteria, in which strokes with unclear aetiology are classified as cryptogenic strokes. However, the definition of cryptogenic stroke did not ...

    • A score to predict one-year risk of recurrence after acute ischemic stroke 

      Strambo D., Zachariadis A., Lambrou D., Schwarz G., Sirimarco G., Aarnio K., Putaala J., Ntaios G., Vemmos K., Michel P. (2021)
      Background: An acute ischemic stroke carries a substantial risk of further recurrences. We aimed at developing and validating a prognostic tool to predict one-year stroke recurrence after acute ischemic stroke. Methods: ...

    • Statin-based therapy for primary and secondary prevention of ischemic stroke: A meta-analysis and critical overview 

      Milionis H., Ntaios G., Korompoki E., Vemmos K., Michel P. (2020)
      Background and aims: To reassess the effect of statin-based lipid-lowering therapy on ischemic stroke in primary and secondary prevention trials with regard to achieved levels of low-density lipoprotein-cholesterol in view ...