Πλοήγηση ανά Θέμα "HUMAN-IMMUNODEFICIENCY-VIRUS"
Αποτελέσματα 1-7 από 7
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Effect of hepatitis C virus on immunological and virological responses in HIV-infected patients initiating highly active antiretroviral therapy: a meta-analysis
(2013)Co-infection of human immunodeficiency virus (HIV) with hepatitis C virus (HCV) is rather common. In the era of highly active antiretroviral therapy (HAART), viral hepatitis could result in adverse outcomes in HIV+ patients. ... -
Electrostatic modeling of peptides derived from the V3-loop of HIV-1 gp120: Implications of the interaction with chemokine receptor CCR5
(2007)Infection of CD4(+) T cells by macrophage-tropic HIV-1 strains involves interaction of viral gp 120 with the host cell chemokine receptor CCR5. The principle neutralizing determinant (PND) of the V3-loop of the HIV-1 gp120 ... -
The HIV-1 gp120/V3 modifies the response of uninfected CD4 T cells to antigen presentation: mapping of the specific transcriptional signature
(2011)Background: The asymptomatic phase of HIV-1 infection is characterized by a progressive depletion of uninfected peripheral effector/memory CD4+ T cells that subsequently leads to immune dysfunction and AIDS symptoms. We ... -
HIV-1 gp120/V3-derived epitopes promote activation-induced cell death to superantigen-stimulated CD4(+)/CD45RO(+) T cells
(2007)The third hypervirable (V3) domain of the HIV-1 envelope glycoprotein gp120 has been implicated in HIV pathogenesis via co-receptor usage of chemokine receptors CCR5 and CXCR4. As the protagonist cell populations in the ... -
HIV-1 infection: Is it time to reconsider our concepts?
(2006)The long asymptomatic phase of HIV infection is critical in the progression to AIDS. It probably reflects an ancestral relationship with lentiviruses stemming from the primate-simian immunodeficiency virus evolutionary ... -
Infections in hemodialysis: a concise review. Part II: blood transmitted viral infections
(2011)Hemodialysis (HD) patients are particularly predisposed to infections. It seems that the HD procedure per se as well as disturbances in both innate and adaptive immunity significantly contribute to this susceptibility. ... -
RNA-Mediated therapeutics: From gene inactivation to clinical application
(2006)The specific targeting and inactivation of gene expression represents nowdays the goal of the mainstream basic and applied biomedical research. Both researchers and pharmaceutical companies, taking advantage of the vast ...