Πλοήγηση ανά Θέμα "GENETIC ASSOCIATION"
Αποτελέσματα 1-8 από 8
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AQP4 Tag Single Nucleotide Polymorphisms in Patients with Traumatic Brain Injury
(2014)Accumulating evidence suggests that the extent of brain injury and the clinical outcome after traumatic brain injury (TBI) are modulated, to some degree, by genetic variants. Aquaporin-4 (AQP4) is the predominant water ... -
Association of tau haplotype-tagging polymorphisms with Parkinson's disease in diverse ethnic Parkinson's disease cohorts
(2006)Background: The overlap in the clinical and pathological features of tauopathies and synucleinopathies raises the possibility that the tau protein may be important in Parkinson's disease (PD) pathogenesis. Several MAPT ... -
Association of TLR4-T399I Polymorphism with Chronic Obstructive Pulmonary Disease in Smokers
(2009)Tobacco smoking has been considered the most important risk factor for chronic obstructive pulmonary disease (COPD) development. However, not all smokers develop COPD and other environmental and genetic susceptibility ... -
Gamma-aminobutyric acid A receptor, alpha-2 (GABRA2) variants as individual markers for alcoholism: a meta-analysis
(2012)Objectives The available evidence from the genetic association studies (GAS) published to date on the association between variants in the GABRA2 gene and alcoholism has produced inconclusive results. To interpret these ... -
Genomic Convergence of Genome-wide Investigations for Complex Traits
(2009)Genome-wide investigations for identifying the genes for complex traits are considered to be agnostic in terms of prior assumptions for the responsible DNA alterations. The agreement of genome-wide association studies ... -
Lack of association of single nucleotide polymorphism in LRCH1 with knee osteoarthritis susceptibility
(2008)A genetic association of knee osteoarthritis (OA) and a C/T transition single nucleotide polymorphism (SNP) (rs912428) located in intron 1 of the LRCH1 gene has recently been reported in European Caucasians; however, the ... -
Performance of MAX Test and Degree of Dominance Index in Predicting the Mode of Inheritance
(2012)We evaluate power performance to detect the correct mode of inheritance in gene-disease associations of two different approaches: the MAX test and the degree of dominance index or h-index. The MAX test is a special case ...