Anzeige der Dokumente 1-11 von 11

    • Aberrant methylation of c-myc and c-fos protooncogenes and p53 tumor suppressor gene in myelodysplastic syndromes and acute non-lymphocytic leukemia 

      Papaggeli, P. C.; Kortsaris, A. C.; Matsouka, P. T. (2003)
      Purpose: Aberrant methylation, as an epigenetic phenomenon, may precede and regulate the expression of genes involved in transformation mechanisms that lead to leukemogenesis of hemopoietic cells. The genes involved mostly ...
    • Association of maternal angiotensin II type 1 and type 2 receptor combination genotypes with susceptibility to early-onset preeclampsia 

      Satra M., Samara M., Alatsathianos G., Vamvakopoulou D., Baka A., Tsalazidou-Founta T.-M., Sidiropoulos A., Vamvakopoulos K.-O., Garas A., Daponte A., Vamvakopoulos N., Sotiriou S. (2022)
      Allelic variations affecting the activity of the maternal renin-angiotensin system may play a role in the development of hypertensive disorders of pregnancy like preeclampsia, its more severe early-onset form, and intrauterine ...
    • CYP1A2 rs762551 and ADORA2A rs5760423 Polymorphisms in Patients with Blepharospasm 

      Siokas V., Kardaras D., Aloizou A.-M., Liampas I., Papageorgiou E., Drakoulis N., Tsatsakis A., Mitsias P.D., Hadjigeorgiou G.M., Tsironi E.E., Dardiotis E. (2020)
      Blepharospasm (BSP) is a neurological movement disorder. Coffee consumption has been found to have a protective effect against BSP. BSP and apraxia of eyelid opening are particularly common among patients with PD. The ...
    • Does the CD33 rs3865444 Polymorphism Confer Susceptibility to Alzheimer’s Disease? 

      Siokas V., Aslanidou P., Aloizou A.-M., Peristeri E., Stamati P., Liampas I., Arseniou S., Drakoulis N., Aschner M., Tsatsakis A., Mitsias P.D., Bogdanos D.P., Hadjigeorgiou G.M., Dardiotis E. (2020)
      Alzheimer’s disease (AD) is a complex genetic disorder. To date, published data have reported conflicting results on the role of CD33 rs3865444 polymorphism in AD. The present study aimed at evaluating the effect of rs3865444 ...
    • Experimental study of the potential role of salmonella enterica subsp. Diarizonae in the diarrhoeic syndrome of lambs 

      Chatzopoulos D.C., Vasileiou N.G.C., Ioannidi K.S., Katsafadou A.I., Mavrogianni V.S., Michael C.K., Katsarou E.I., Karavanis E., Papadopoulos N., Sbiraki A., Athanasiou L.V., Billinis C., Fthenakis G.C. (2021)
      The objectives of this experimental work were the evaluation of the potential role of Salmonella enterica subsp. diarizonae in diarrhoeic syndrome in lambs and the investigation of facets of the pathogenesis of the infection. ...
    • Genetic profiling and volatile oil content of oregano genotypes from greece 

      Papaioannou C., Stefanakis M.K., Batargias C., Kilias G., Anastasopoulos E., Katerinopoulos H.E., Papasotiropoulos V. (2020)
      Several oregano genotypes belonging to Origanum vulgare subsp. hirtum (Link) Ietsw., O. onites L., and O. majorana L., Lamiaceae, from Greece, were genetically and chemically studied. Genetic analysis with microsatellite ...
    • Genetic variations in the SULF1 gene alter the risk of cervical cancer and precancerous lesions 

      Dardiotis E., Siokas V., Garas A., Paraskevaidis E., Kyrgiou M., Xiromerisiou G., Deligeoroglou E., Galazios G., Kontomanolis E.N., Spandidos D.A., Tsatsakis A., Daponte A. (2018)
      Human papillomavirus (HPV) infection alone is not sufficient to explain the development of cervical cancer. Genetic variants have been linked to the development of precancerous lesions and cervical cancer. In this study, ...
    • Renin-angiotensin system single nucleotide polymorphisms are associated with bladder cancer risk 

      Samara M., Papathanassiou M., Farmakioti I., Anagnostou M., Satra M., Mitrakas L., Anastasiou D., Chasiotis G., Christopoulos A., Anagnostou A., Christodoulou A., Daponte A., Ioannou M., Koukoulis G., Tzortzis V., Vlachostergios P.J. (2021)
      The renin-angiotensin system (RAS), besides being a major regulator of blood pressure, is also involved in tumor angiogenesis. Emerging evidence suggests a correlation between the use of pharmacologic RAS inhibitors and a ...
    • Risk Factor Assessment in a Greek Cohort of Patients With Large Abdominal Aortic Aneurysms 

      Makrygiannis G., Mourmoura E., Spanos K., Roussas N., Kuivaniemi H., Sakalihasan N., Tsezou A., Giannoukas A. (2019)
      Environmental and genetic risk factors contribute to the etiology of abdominal aortic aneurysms (AAAs). Matrix metalloproteinases (MMPs) have been associated with the pathophysiology of AAAs. A prospective, nonrandomized ...
    • SLC2A3 rs12842 polymorphism and risk for Alzheimer’s disease 

      Arseniou S., Siokas V., Aloizou A.-M., Stamati P., Mentis A.-F.A., Tsouris Z., Dastamani M., Peristeri E., Valotassiou V., Bogdanos D.P., Hadjigeorgiou G.M., Dardiotis E. (2020)
      Background: Many studies support the hypothesis that brain glucose dysregulation contributes to neurodegeneration and disease progression. The SLC2A3 gene encodes the Neuronal Glucose Transporter 3 (GLUT3), a critical ...
    • Val66Met polymorphism is associated with decreased likelihood for pediatric headache and migraine 

      Koute V., Michalopoulou A., Siokas V., Aloizou A.-M., Rikos D., Bogdanos D.P., Kontopoulos E., Grivea I.N., Syrogiannopoulos G.A., Papadimitriou A., Hadjigeorgiou G.M., Dardiotis E. (2021)
      Background: Migraine is a complex multifactorial disorder and its pathogenesis still remains unclear. Evidence suggests the involvement of the activated trigeminovascular pathway, in which BDNF seems to play an important ...